亚洲女性剖宫产腰麻药物的注射速度和低血压发生率的相关性研究与分析  

Correlation and analysis of the injection rate of narcotic drugs and the incidence of hypotension in cesarean section in Asian women

作　　者：陈辉[1] 李琦[1] 吴琼[1] CHEN Hui;LI Qi;WU Qiong(Wuhan Hanyang Hospital,Wuhan 430050,China)

机构地区：[1]武汉科技大学附属汉阳医院,武汉430050

出　　处：《长春中医药大学学报》2020年第5期1006-1008,共3页Journal of Changchun University of Chinese Medicine

基　　金：湖北省卫生健康委员会科研项目(WJ2019F015)。

摘　　要：目的观察麻醉药物的注射速度对于产妇低血压的影响。方法本研究纳入了50例剖宫产产妇,将其随机分为快速注射组和慢速注射组,各25例。分别以快速(10~15 s)和慢速(120 s)注射重比重布比卡因10 mg、舒芬太尼2 mg和吗啡200 mg(总体积4 mL)。低血压的定义为动脉收缩压(SAP)<100 mg或<70%基线水平。如果发生低血压则立即给予静脉推注5 mg肾上腺素,直至血压恢复正常。结果与快速注射组相比较,慢速注射组的低血压的发生率明显降低(P=0.03)。慢速注射组的低血压的发生时间延迟,持续时间较短,所需麻黄碱的剂量明显减少(P=0.019)。结论以2 mL·min^-1的速度注射腰麻药物可以明显降低腰麻下剖宫产术中的低血压发生率。Objective Maternal hypotension was a common clinical problem in the process of cesarean section.The present study was a prospective,observational study of the effects of the rate of anesthetic injection on maternal hypotension.Methods A total of 50 women who underwent elective cesarean section were divided randomly into the rapid-injection group(n=25)and the slowinjection group(n=25).The high weigh proportion bupivacaine 10 mg,sufentanil 2 mg,and morphine 200 mg(total volume 4 mL)were injected rapidly(15 s)and slowly(120 s),respectively.Hypotension was defined as systolic arterial pressure(SAP)<100 mmHg or<70%baseline value.If hypotension occured,an intravenous bolus of 5 mg of ephedrine was given immediately until the blood pressure returned to the normal value.Results The incidence of hypotension was significantly reduced in the slowinjection group compared with that of the fast-injection group(P<0.03).In addition,the hypotensive time of the slow-injection group was delayed,with a shorter duration,and the dose of ephedrine required was significantly reduced(P<0.019).Conclusion Injection of spinal anesthetics at a rate of 2 mL/min can significantly reduce the incidence of hypotension during cesarean section under spinal anesthesia.

关 键 词：剖宫产 腰麻 低血压 注射速度 

分 类 号：R614[医药卫生—麻醉学]