171例输血反应影响因素分析  

Analysis of the influencing factors on adverse reactions to blood transfusion:a retrospective study of 171 cases

作　　者：吴瑛 谭春泽 杨雪 傅明玮 禹亚丽 唐岸柳 刘丽娟 刘易娟 王林 罗成 杨凯 王继任 李聚林 WU Ying;TAN Chunze;YANG Xue;FU Mingwei;YU Yali;TANG AnliuLIU Lijuan;LIU Yijuan;WANG Lin;LUO Cheng;YANG Kai;WANG Jiren;LI Julin(Department of Blood Transfusion,924th Hospital of People's Liberation Army Joint Support Force,Guilin Blood Station of People's Liberation Army,Guilin 541002,China;Guangxi Blood Center.)

机构地区：[1]解放军联勤保障部队第九二四医院输血科解放军桂林血站,广西桂林541002 [2]广西血液中心

出　　处：《中国输血杂志》2020年第7期673-676,共4页Chinese Journal of Blood Transfusion

基　　金：广西医药卫生课题(Z20170978)。

摘　　要：目的探讨输血反应相关的影响因素,保障临床输血安全。方法从医院或(和)输血科信息管理系统记录的本院2001—2018年各临床用血科室的62 399例输血病例(历)中,收集记录为输血反应的病例171例,回顾性调查分析输血反应类型,以及输血者年龄、性别与输血前预防用药、输血史或(和)妊娠史、输注成分血和临床用血科室对输血反应的影响,采用χ~2检验结合Logistic回归分析找出影响输血反应的相关因素。结果本(院)组8年间的输血反应率为0.27%(171/62 399),其中过敏反应占67.84%(116/171)、发热反应24.56%(42/171)、其他反应7.60%(13/171)。影响患者输血反应的因素有输注的成分血、输血前预防用药(P<0.05)。结论输注的成分血、输血前预防用药可能是输血反应的重要独立影响因素;对此制定个体化科学输血措施,有助于确保临床输血安全与实现精准输血。Objective To explore the influencing factors related to adverse reaction to blood transfusion(ARBD),so as to make efforts in ARBD precautions and ensure the safety of clinical blood transfusion.Methods According to the 62399 blood transfusion records of our hospital from 2001 to 2018 available at the information management system of hospital or(and)Blood Transfusion Department,171 cases of ARBD occurred.The types of ARBD,age,gender,pre-transfusion preventive medication,history of blood transfusion or(and)the history of pregnancy,the blood component transfused and clinical blood department were investigated retrospectively and analyzed,usingχ2 test combined with Logistic regression analysis,in order to find out the influencing factors of ARBD.Results The incidence of ARBD in our hospital throughout 8 years was 0.27%(171/62399),of which allergic reactions accounted for 67.84%(116/171),fever reactions 24.56%(42/171),and other reactions 7.60%(13/171).The factors related to ARBD included the blood components of the transfusion and the pre-transfusion preventive medication(P<0.05).Conclusion The blood components transfused and pre-transfusion preventive medications might be the important independent influencing factors of ARBD.The development of individualized blood transfusion strategies targeting at the influencing factors is helpful to ensure the safety of clinical blood transfusion and achieve accurate blood transfusion.

关 键 词：输血反应 过敏 发热 输注成分血 预防用药 影响因素 

分 类 号：R457.13[医药卫生—治疗学]