Population normative models of human brain growth across development  被引量:2

人脑生长发育的群体常模

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作  者:Bharath Holla Jakob Seidlitz Richard A.I.Bethlehem Gunter Schumann 

机构地区:[1]Departments of Psychiatry and Integrative Medicine,National Institute of Mental Health and Neuro Sciences(NIMHANS),Bengaluru 5600029,India [2]Department of Child and Adolescent Psychiatry and Behavioral Science,Children’s Hospital of Philadelphia,Philadelphia,PA 19104,USA [3]Department of Psychiatry,University of Pennsylvania,Philadelphia,PA 19104,USA [4]Autism Research Centre,Department of Psychiatry,University of Cambridge,Cambridge CB28AH,UK [5]Brain Mapping Unit,Department of Psychiatry,University of Cambridge,Cambridge CB28AH,UK [6]Centre for Population Neuroscience and Stratified Medicine(PONS),SGDP Centre,IoPPN,KCL,London SE58AF,UK [7]PONS-Centre,Dept of Psychiatry and Psychotherapy,Campus Charite Mitte,Humboldt University,Berlin D 10117,Germany [8]PONS Centre,Institute for Science and Technology of Brain-inspired Intelligence(ISTBI),Fudan University,Shanghai 200433,China

出  处:《Science Bulletin》2020年第22期1872-1873,M0003,共3页科学通报(英文版)

基  金:the Horizon 2020 funded ERC Advanced Grant“STRATIFY”(Brain network based stratification of reinforcement-related disorders)(695313);Human Brain Project(HBP SGA 3945539);the Medical Research Council Grant“c-VEDA”(Consortium on Vulnerability to Externalizing Disorders and Addictions)(MR/N000390/1);the NIH Consortium grant U54 EB020403;supported by a cross-NIH alliance that funds Big Data to Knowledge Centres of Excellence;Jakob Seidlitz is supported by a Ruth L.Kirschstein Institutional National Research Service Award(NRSA)research training grant(Parent T32);Richard A.I.Bethlehem is supported by a British Academy Post-Doctoral Fellowship and the Autism Research Trust;Bharath Holla is partly supported by DBT(BT/PR17316/MED/31/326/2015);Accelerator Program for Discovery in Brain Disorders using Stem Cells and c-VEDA(Consortium on Vulnerability to Externalizing Disorders and Addictions-Grant:ICMR/MRC-UK/3/M/2015-NCD-I)。

摘  要:Growth charts for gross anthropometric traits,such as height,weight,and head circumference,are cornerstones of pediatric care around the world.This modelling approach is centered around measuring the relative deviations from normative trajectories rather than the absolute values of these phenotypes[1].To this end,it is imperative that normative models are not only robust in terms of the statistical framework on which they are built。

关 键 词:CORNERS ABSOLUTE ANT 

分 类 号:R338[医药卫生—人体生理学]

 

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