世居高原颅脑肿瘤患者在平原手术相关血液学指标的分析  

Analysis of hematological index related to plain surgery in patients with intracranial tumor living on the plateau

作　　者：罗强[1] 刘卫平 龙乾发[1] 张胡金[1] 柴源 苗宇 伊西才 LUO Qiang;LIU Weiping;LONG Qianfa;ZHANG Hujin;CHAI Yuan;MIAO Yu;YI Xicai(Department of Neurosurgery,Central Hospital of Xi′an,Xi′an 710003,China;Department of Neurosurgery,Xijing Hospital of Air Force Military Medical University)

机构地区：[1]西安市中心医院神经外科,陕西西安710003 [2]空军军医大学西京医院神经外科

出　　处：《西北国防医学杂志》2020年第10期638-641,共4页Medical Journal of National Defending Forces in Northwest China

摘　　要：目的:探讨世居高原颅脑肿瘤患者移至平原进行手术后相关血液学指标的差异。方法:选择2009-01~2016-05收治的来自青海省高原地区(平均海拔3245 m)的45例颅脑肿瘤患者为观察组,同期来自本地(平均海拔400 m)的45例颅脑肿瘤患者为对照组。测定两组术前及术后3 d手术相关血液学指标,并进行对比分析,包括红细胞(red blood cells,RBC)、血红蛋白(hemoglobin,HGB)、血细胞比容(hematocrit,HCT)、血小板(platelet,PLT)、血浆纤维蛋白原含量(fibrinogen,FIB)和凝血酶原时间(prothrombin time,PT)。结果:观察组术前、术后3 d的RBC、HGB、HCT高于对照组(均P<0.01),PLT低于对照组(P<0.05)。观察组术后3 d的RBC、HGB、HCT、PT仍低于术前(均P<0.05),FIB高于术前(P<0.05)。结论:高原颅脑肿瘤患者移至平原后RBC、HCT、PLT等血液学指标与平原患者相比存在显著差异,可能对其手术安全性造成一定的影响,应高度重视并积极防治以降低高原患者在平原手术的潜在风险。Objective:To explore the hematological index differences related to plain surgery in patients with intracranial tumor living on the plateau.Methods:Forty-five patients with intracranial tumor from January 2009 to May 2016 from Qinghai(average altitude 3245 m)were selected as observation group,and at same time forty-five local patients with intracranial tumor(average altitude 400 m)were selected as control group.The hematological index respectively in pre-operation and post-operation 3 days were analyzed,including red blood cells(RBC),hemoglobin(HGB),hematocrit(HCT),platelet(PLT),fibrinogen(FIB),prothrombin time(PT).Results:The RBC,HGB,HCT of the observation group in pre-operation and post-operation 3 days were significantly higher than those of the control group(P<0.01),the PLT was lower than that of the control group(P<0.05).The RBC,HGB,HCT,PT of the observation group in post-operation 3 days were significantly lower than those in pre-operation(P<0.05),the FIB was significantly higher than that in pre-operation(P<0.05).Conclusion:There are differences in hematological index between the plateau patients and the plain patients,which can cause some impact to surgery.We should attach great importance to these differences to reduce the risk of plain surgery in intracranial tumor patients living on the plateau.

关 键 词：高原 颅脑肿瘤 血液学 手术 

分 类 号：R81[医药卫生—放射医学]