应用Gd-EOB-DTPA增强MRI评价肝功能的研究进展  

Research progress of Gd-EOB-DTPA enhanced MRI in evaluating liver function

作　　者：邵佳 贺业新 SHAO Jia;HE Yexin(Shanxi Medical University,Taiyuan 030001,China;Department of MRI,Affiliated People's Hospital of Shanxi Medical University,Taiyuan 030012,China)

机构地区：[1]山西医科大学,太原030001 [2]山西医科大学附属人民医院磁共振室,太原030012

出　　处：《磁共振成像》2020年第11期1056-1058,共3页Chinese Journal of Magnetic Resonance Imaging

摘　　要：磁共振成像在检测肝脏疾病中具有重要作用,钆塞酸二钠(Gadoliniumethoxybenzyl-diethylenetriamine pentaacetic acid,Gd-EOB-DTPA)是目前临床上常用的肝脏特异性磁共振对比剂之一,不仅对肝脏局灶性结节的检出具有重要意义,而且对肝脏弥漫性病变肝功能的评估具有潜在的应用价值,基于解剖学信息基础上定量评估不同肝段肝功能对于慢性肝病及肝癌患者选择合适治疗手段更为重要。近年来,Gd-EOB-DTPA增强磁共振成像在临床中应用越来越广泛,其评估肝功能的方式主要包括增强前、后MR弛豫时间的测定、肝实质信号强度的变化、胆管信号强度、胆管显影时间以及胆管内对比剂排泄量的测定等。作者就Gd-EOB-DTPA增强磁共振成像对肝功能诊断价值的相关研究进行综述。Magnetic resonance imaging plays an important role in the detection of liver diseases.Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid(Gd-EOB-DTPA)is one of the commonly used liver-specific contrast agents in clinical practice.It is not only of great significance in the detection of focal lesions,but also of potential application value in the assessment of diffuse liver damage.Quantitative evaluation of liver function in different segments based on anatomical information is more important for the selection of appropriate treatment for patients with chronic liver disease and liver cancer.In recent years,Gd-EOBDTPA-enhanced magnetic resonance imaging has become more and more widely used in clinical practice,and its methods for assessing liver function mainly include measurement of relaxation time before and after enhanced,changes in liver parenchymal signal intensity,the biliary tract signal intensity and bile duct imaging time and measurement of contrast agent in bile duct.This article reviews the related research on the diagnostic value of Gd-EOB-DTPA enhanced magnetic resonance imaging for liver function.

关 键 词：肝功能试验 顺磁性对比剂 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R657.51[医药卫生—诊断学]