冠心病诊断中血清胆红素与尿酸检验的应用价值  

Application Value of Serum Bilirubin and Uric Acid Test in the Diagnosis of Coronary Heart Disease

作　　者：莫超云 严子泳 梁羡方 MO Chaoyun;YAN Ziyong;LIANG Xianfang(Laboratory Department,Yangdong District People’s Hospital of Yangjiang City,Yangjiang Guangdong 529500,China;Department of Cardiovascular Medicine,Yangdong District People’s Hospital of Yangjiang City,Yangjiang Guangdong 529500,China)

机构地区：[1]阳江市阳东区人民医院检验科,广东阳江529500 [2]阳江市阳东区人民医院心血管内科,广东阳江529500

出　　处：《中国继续医学教育》2020年第31期104-107,共4页China Continuing Medical Education

摘　　要：目的探讨冠心病患者血清胆红素与尿酸检验的应用价值。方法回顾性选取2017年10月—2019年10月医院冠心病患者70例,将这些患者作为冠心病组,另回顾性选取同期医院健康体检人员70例作为健康组,运用尿酸检测试剂盒(比色法)Uric Acid ver.2(UA2)(规格:1000测试,批号:39142101)检测尿酸水平,运用总胆红素检测试剂盒(重氮法)Bilirubin Total(规格:600测试,批号:36135401)检测血清胆红素水平,然后统计分析两组人员的血清胆红素与尿酸水平、冠心病组不同病变程度患者的血清胆红素与尿酸水平。结果冠心病组患者的血清直接、间接胆红素、总胆红素水平均显著低于健康组(P<0.05),尿酸水平显著高于健康组(P<0.05)。冠心病组患者70例中,轻度狭窄23例,中度狭窄18例,重度狭窄17例,极重度狭窄12例,分别占32.9%、25.7%、24.3%、17.1%,其血清直接胆红素、间接胆红素、总胆红素水平均逐渐降低(P<0.05),尿酸水平逐渐升高(P<0.05)。结论冠心病患者血清胆红素与尿酸检验的应用价值高。Objective To explore the application value of serum bilirubin and uric acid test of patients with coronary heart disease.Methods 70 cases of patients with coronary heart disease in our hospital from October 2017 to October 2019 were selected as coronary heart disease group,and 70 cases of healthy people in our hospital were selected as healthy group.The serum uric acid level was measured by Uric acid ver.2(UA2)(specification:1000 test,batch number:39142101),the serum bilirubin level was measured by bilirubin Total(specification:600 test,batch number:36135401),and then the serum bilirubin and uric acid levels of the two groups,the levels of serum bilirubin and uric acid levels of patients with different pathological changes in the coronary heart disease group were statistically analyzed.Results The serum levels of direct,indirect and total bilirubin of the coronary heart disease group were significantly lower(P<0.05),the uric acid level was significantly higher than the healthy group(P<0.05).Among the 70 cases of patients in the coronary heart disease group,23 cases were mild stenosis,18 cases were moderate stenosis,17 cases were severe stenosis and 12 cases were extremely severe stenosis,accounting for 32.9%,25.7%,24.3%and 17.1%respectively.The levels of serum direct bilirubin,indirect bilirubin and total bilirubin decreased gradually(P<0.05),the levels of urine acid increased gradually(P<0.05).Conclusion The application value of serum bilirubin and uric acid test of patients with coronary heart disease is high.

关 键 词：冠心病 血清胆红素 尿酸 重氮法 比色法 应用价值 

分 类 号：R541[医药卫生—心血管疾病]