舍曲林联合正念治疗对于PCI术后焦虑障碍的疗效分析  

Effect of Sertraline Combined With Mindfulness on Anxiety Disorder After PCI

作　　者：陈波[1] 张集慧[1] 张忠良 唐旭 CHEN Bo;ZHANG Jihui;ZHANG Zhongliang;TANG Xu(Department of Psychological Rehabilitation,The Third Affiliated Hospital of Baotou Medical College,Baotou Inner Mongolia 014030,China)

机构地区：[1]包头医学院第三附属医院心理康复科,内蒙古包头014030

出　　处：《中国继续医学教育》2020年第31期131-134,共4页China Continuing Medical Education

摘　　要：目的讨论舍曲林联合正念治疗对PCI术后患者焦虑障碍的治疗效果。方法选取医院2017年3月—2019年3月收治的60例经皮冠状脉介入(PCI)手术治疗的冠心病患者,采取随机抽签的方式分为A组和B组,A组采用舍曲林联合正念治疗,B组采用舍曲林治疗,每组各30例,疗程为8周。运用汉密顿焦虑量表(HAMA)、汉密顿抑郁量表(HAMD)对患者的临床疗效和不良反应进行评价。结果A组采取舍曲林合并正念治疗的方法,HAMA评分治疗前为(17.80±1.39)分,治疗后评分为(8.77±2.32)分;HAMD治疗前评分为(17.82±0.93)分,治疗后评分为(9.85±0.77)分。B组患者采用舍曲林治疗,HAMA评分治疗前为(18.23±2.31)分,治疗后评分为(11.42±2.43)分;HAMD治疗前评分为(18.45±1.32)分,治疗后评分为(12.14±1.81)分。A组显著优于B组,说明舍曲林合并正念治疗的方法对患者的治疗效果非常明显。A组总有效率为93.33%,B组总有效率为60.00%。A组高于B组,P<0.05,差异具有统计学意义。结论舍曲林联合正念治疗,对PCI术后焦虑障碍具有非常明显的诊疗效果,安全性更高、依从性更好。Objective To discuss the therapeutic effect of sertraline combined with mindfulness therapy on anxiety disorder of patients after PCI.Methods 60 patients with coronary heart disease treated by percutaneous coronary intervention(PCI)from March 2019 to March 2020 in our hospital were selected and randomly divided into group A and group B with 30 patients in each group for 8 weeks.Group A was treated with sertraline combined with mindfulness therapy,and group B was treated with sertraline.Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)were used to evaluate the clinical efficacy and adverse reactions of patients.Results Group A was treated with sertraline combined with mindfulness.HAMA score was(17.80±1.39)before treatment and(8.77±2.32)after treatment.HAMD score was(17.82±0.93)before treatment and(9.85±0.77)after treatment.The HAMA score of group B patients(used Sertraline)was(18.23±2.31)before treatment and(11.42±2.43)after treatment.HAMD score was(18.45±1.32)before treatment and(12.14±1.81)after treatment.Group A is better than Group B,which shows that sertraline combined with mindfulness therapy has a very obvious therapeutic effect on patients.The total effective rate in group A was 93.33%,while that in group B was 60.00%.Group A is higher than group B,P<0.05,which is comparable.Conclusion Sertraline combined with mindfulness therapy has very obvious therapeutic effect on anxiety disorder after PCI,with higher safety and better compliance,which is worthy of clinical promotion.

关 键 词：舍曲林 正念治疗 PCI手术 焦虑障碍 心理治疗 治疗效果 

分 类 号：R541[医药卫生—心血管疾病]