磁共振成像发展综述  

Magnetic resonance imaging:progresses and perspective

作　　者：高家红 雷皓 陈群 杜一平 梁栋[5] 卓彦[6] 龚启勇[7] 周欣 GAO JiaHong;LEI Hao;CHEN Qun;DU YiPing;LIANG Dong;ZHUO Yan;GONG QiYong;ZHOU Xin(Center for MRI Research,Beijing City Key Lab for Medical Physics and Engineering,Institution of Heavy Ion Physics,School of Physics,Peking University,Beijing 100871,China;National Center for Magnetic Resonance in Wuhan,State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics,Innovation Academy for Precision Measurement Science and Technology,Chinese Academy of Sciences,Wuhan 430071,China;Shanghai United Imaging Healthcare Co.,Ltd.,Ltd.,Shanghai 201807,China;School of Biomedical Engineering,Shanghai Jiao Tong University,Shanghai 200030,China;Paul C.Lauterbur Research Center for Biomedical Imaging,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen,China,CAS key Laboratory of Health Informatics,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China;State Key Laboratory of Brain and Cognitive Science,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China;Huaxi MR Research Center(HMRRC),Department of Radiology,West China Hospital of Sichuan University,University,Chengdu 610041,China)

机构地区：[1]北京大学物理学院医学物理和工程北京市重点实验室北京大学前沿交叉学科研究院磁共振成像研究中心,北京100871 [2]中国科学院精密测量科学与技术创新研究院波谱与原子分子物理国家重点实验室武汉磁共振中心,武汉430071 [3]上海联影医疗科技有限公司联影研究院 [4]上海交通大学生物医学工程学院 [5]中国科学院深圳先进技术研究院生物医学与健康工程研究所 [6]中国科学院生物物理研究所脑与认知国家重点实验室 [7]四川大学华西医院放射科华西磁共振研究中心

出　　处：《中国科学：生命科学》2020年第11期1285-1295,共11页Scientia Sinica(Vitae)

摘　　要：磁共振成像(magnetic resonance imaging,MRI)是目前临床医学诊断和基础生命科学研究中最重要的影像学工具之一,具有无损无创、软组织对比度高、成像参数和对比度众多、图像信息丰富等特点.近年来,磁共振成像在仪器技术和应用研究方面都取得了飞速的发展.超高场强、超快速和超灵敏磁共振成像等一批尖端成像技术正在走向临床,并与大数据、人工智能、诊疗一体化等其他先进技术相互渗透、相互融合.在应用研究方面,磁共振成像在肿瘤分子影像、脑功能成像、脑连接组研究等方面也正发挥着越来越重要的作用.本文简介了磁共振成像发展历史及基本原理,梳理了磁共振成像仪器技术、方法学和应用研究中的关键科学问题,提出了我国磁共振成像研究的发展思路和重点研究方向.Magnetic resonance imaging(MRI)as one of the most important imaging methods is widely used in clinical diagnosis and basic life science research,with advantages including noninvasiveness,high/multiple soft tissue contrast,parametric imaging and the richness of information.During recent years,there have been many advances in the instrument technology and biomedical application of MRI.Advanced techniques,such as ultra-high field,ultra-fast and ultra-sensitive imaging,are now available for routine clinical usage and research settings.Also,the MRI technology is rapidly developing via incorporating with multiple cutting-edge disciplines including big data technology,artificial intelligence and theranostics.Currently,MRI is playing an indispensable role in tumor molecular imaging,functional brain imaging and brain connectome studies.This paper introduces the history and basic principles of MRI,and summarizes the important problems in the research of MRI instrument,methodology and application,providing a perspective on the directions of future MRI research in China.

关 键 词：磁共振成像 高场强 压缩感知 人工智能 诊疗一体化 脑科学 

分 类 号：R445.2[医药卫生—影像医学与核医学]