针刺配合药物治疗甲状腺结节的疗效观察  

Therapeutic Observation of Acupuncture Combined with Medication for Thyroid Nodules

作　　者：厉馨 陈敬博 杨百京[2] LI Xin;CHENJing-bo;YANG Bai-jing(Xinjiang Uighur Municipal People’s Hospital,Urumqi 830001,China;First Affiliated Hospital,School of Medicine,Shihezi University,Shihezi 832000,China)

机构地区：[1]新疆维吾尔自治区人民医院,乌鲁木齐830001 [2]石河子大学医学院第一附属医院,石河子832000

出　　处：《上海针灸杂志》2020年第11期1366-1370,共5页Shanghai Journal of Acupuncture and Moxibustion

基　　金：全国名老中医药专家传承工作室建设项目[国中医人教发2014(20)号]。

摘　　要：目的观察针刺配合药物治疗甲状腺结节的临床疗效。方法将116例甲状腺结节患者随机分为治疗组和对照组,每组58例。对照组采用口服加味柴胡桂枝汤配合左甲状腺素钠片治疗,治疗组在对照组基础上采用针刺治疗。观察两组治疗前后各项甲状腺功能指标[游离三碘甲状腺原氨酸(FT3)、游离四碘甲状腺原氨酸(FT4)、促甲状腺激素(TSH)]、甲状腺结节情况(大小、数量及体积)及中医证候评分的变化情况,并比较两组临床疗效。结果两组治疗后TSH水平、甲状腺结节情况及中医证候评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后TSH水平、甲状腺结节情况及中医证候评分与对照组比较,差异均具有统计学意义(P<0.05)。治疗组总有效率为93.1%,对照组为79.3%,两组比较差异具有统计学意义(P<0.05)。结论针刺配合药物治疗甲状腺结节疗效确切,能改善患者甲状腺结节的直径、数量、体积。Objective To observe the clinical efficacy of acupuncture plus medication in treating thyroid nodules.Method A total of 116 patients with thyroid nodules were randomized into a treatment group and a control group,with 58 cases in each group.The control group was intervened by oral administration of Jiawei Chaihu Guizhi decoction plus Levothyroxine sodium tablets,while the treatment group was given additional acupuncture intervention.The thyroid function indicators[free triiodothyronine(FT3),free tetraiodothyronine(FT4)and thyroid-stimulating hormone(TSH)],descriptions of the thyroid nodules(size,number and volume)and symptom score of traditional Chinese medicine(TCM)were observed before and after treatment in the two groups.The clinical efficacy was also compared between the two groups.Result The TSH level,thyroid nodule descriptions and TCM symptom score changed significantly after treatment in the two groups(P<0.05).After treatment,The TSH level,thyroid nodule descriptions and TCM symptom score in the treatment group were significantly different from those in the control group(P<0.05).The total effective rate was 93.1%in the treatment group versus 79.3%in the control group,and the between-group difference was statistically significant(P<0.05).Conclusion Acupuncture plus medication is effective in treating thyroid nodules;it can improve the diameter,number and volume of the thyroid nodules.

关 键 词：针刺疗法 甲状腺结节 针药并用 游离三碘甲状腺原氨酸 游离四碘甲状腺原氨酸 促甲状腺激素 柴胡桂枝汤 

分 类 号：R246.1[医药卫生—针灸推拿学]