Degradation of kanamycin from production wastewater with high-concentration organic matrices by hydrothermal treatment  

作　　者：Mei Tang Fan Li Min Yang Yu Zhang 

机构地区：[1]State Key Laboratory of Environmental Aquatic Chemistry,Research Center for Eco-Environmental Sciences,University of Chinese Academy of Sciences,Chinese Academy of Science,Beijing 100085,China [2]Key Laboratory of Drinking Water Science and Technology,Research Center for Eco-Environmental Sciences,University of Chinese Academy of Sciences,Chinese Academy of Science,Beijing 100085,China [3]National Engineering Laboratory for Industrial Wastewater Treatment,Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing 100085,China

出　　处：《Journal of Environmental Sciences》2020年第11期11-18,共8页环境科学学报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.21590814 and 81861138051)。

摘　　要：It is known that many kinds of fermentative antibiotics can be removed by temperatureenhanced hydrolysis from production wastewater based on their easy-to-hydrolyze characteristics.However,a few aminoglycosides are hard to hydrolyze below 100℃ because of their stability expressed by high molecular energy gap(E).Herein,removal of hard-to-hydrolyze kanamycin residue from production wastewater by hydrothermal treatment at subcritical temperatures was investigated.The results showed the reaction temperature had a significant impact on kanamycin degradation.The degradation half-life(t1/2)was shortened by 87.17-fold when the hydrothermal treatment temperature was increased from 100℃ to 180℃.The t1/2 of kanamycin in the N2 process was extended by 1.08-1.34-fold compared to that of the corresponding air process at reaction temperatures of 140-180℃,indicating that the reactions during hydrothermal treatment process mainly include oxidation and hydrolysis.However,the contribution of hydrolysis was calculated as 75%-98%,which showed hydrolysis played a major role during the process,providing possibilities for the removal of kanamycin from production wastewaters with high-concentration organic matrices.Five transformation products with lower antibacterial activity than kanamycin were identified using UPLC-QTOF-MS analysis.More importantly,hydrothermal treatment could remove 97.9%of antibacterial activity(kanamycin EQ,1,109 mg/L)from actual production wastewater with CODCr around 100,000 mg/L.Furthermore,the methane production yield in anaerobic inhibition tests could be increased about 2.3 times by adopting the hydrothermal pretreatment.Therefore,it is concluded that hydrothermal treatment as a pretreatment technology is an efficient method for removing high-concentration hard-to-hydrolyze antibiotic residues from wastewater with high-concentration organic matrices.

关 键 词：Pharmaceutical wastewater Hydrothermal process Antibiotic antibacterial activity HYDROLYSIS Refractory organic wastewater 

分 类 号：X787[环境科学与工程—环境工程]