宫腔内人工授精结局及其影响因素分析  

Analysis of 136 IUI Cycles to Determine Clinical Outcomes and Its Associated Factors

作　　者：刘旻[1] 单红英[1] 张玉[1] 陈月婵[1] 周侃[1] LIU Min;SHAN Hong-ying;ZHANG Yu;CHEN Yue-chan;ZHOU Kan(Reproductive Department,the First Affiliated Hospital of Shihezi University School of Medicine,Xinjiang Shihezi,832008)

机构地区：[1]石河子大学医学院第一附属医院生殖科,新疆石河子832008

出　　处：《农垦医学》2020年第4期309-312,共4页Journal of Nongken Medicine

摘　　要：目的:探讨新建生殖医学科宫腔内人工授精(IUI)临床结局及其相关影响因素。方法:通过对136个夫精人工授精(AIH)周期与52个供精人工授精(AID)周期的不孕妇女年龄、周期数、不孕原因、治疗方案、精子回收率、注入宫腔内前向运动精子数、实施季节方面临床资料进行回顾性分析,总结上述因素与妊娠率的关系。结果:⑴136个AIH周期的临床妊娠率为:12.50%;52个AID周期的临床妊娠率为:28.85%;⑵AIH女性患者年龄31~35岁的临床妊娠率较高,AID女性患者年龄≤30岁的临床妊娠率较高;⑶IUI自然周期与药物微刺激治疗方案的临床妊娠率相差不大;⑷AIH注入宫腔内前向运动精子数多者妊娠率高,AID精子回收率大于60%者临床妊娠率高;⑸春、夏、秋季施行IUI者妊娠率较高。所有分组临床妊娠率差异均无统计学意义(P>0.05)。结论:通过本次回顾性分析发现IUI临床妊娠率可能与女方年龄、注入宫腔内前向运动精子数、施行季节有相关性,但由于周期数太少,有待加大周期数进一步观察研究。Objective:To analyze the clinical outcomes and related influencing factors of intrauterine insemination(IUI)in new reproductive medicine.Methods:By retrospective analysis the age of infertile women,the number of cycles,the cause of infertility,the treatment plan,the sperm recovery rate,the injection into the intrauterine anterior movement and the implementation season through 136 artificial insemination(AIH)cycles and 52 insemination artificial insemination(AID)cycles,summarized the relationship between these factors and pregnancy rate.Results:(1)The clinical pregnancy rate of 1136 AIH cycles was 12.50%.The clinical pregnancy rate of 52 AID cycles was28.85%.(2)AIH female patients aged 31 to 35 years old have a higher clinical pregnancy rate,AID female patients aged 30 or less 30 years old have a higher clinical pregnancy rate.(3)The clinical pregnancy rate of IUI natural cycle and drug micro-stimulation treatment program is similar.(4)The pregnancy rate was higher in patients with more antegrade motility sperm injected into uterine cavity by AIH,and the clinical pregnancy rate was higher in patients with AID sperm recovery rate greater than 60%.(5)The spring,summer and autumn implementation of IUI pregnancy rate is higher.There was no significant difference in clinical pregnancy rate between all groups(P>0.05).Conclusion:Through this retrospective analysis,we can find that the clinical pregnancy rate of IUI is related to the age of the woman,the number of sperms injected into the uterus,and the season of implementation.However,the number of cycles is too small to further increase the number of cycles.

关 键 词：宫腔内人工授精 临床妊娠率 影响因素 

分 类 号：R714.8[医药卫生—妇产科学]