重组蛋白类药物蛋白含量测定方法探究  

Measurement Method Research Of Protein Content In Recombinant Protein Drugs

作　　者：李昊娜 许宏 LI Hao-na;XU Hong(Shanghai University of Medicine&Health Sciences,Shanghai,201318;Wuwei City Tianzhu Tibetan Autonomous County The First Middle School Of Gansu,Wuwei,Gansu,733200)

机构地区：[1]上海健康医学院,上海201318 [2]甘肃省武威市天祝藏族自治县第一中学,甘肃武威733200

出　　处：《智慧健康》2020年第27期195-197,共3页Smart Healthcare

摘　　要：在生物技术药物质量控制进程中,对蛋白类药物实现精确定量始终是一项重要课题。本文从宏观的角度出发,将测定蛋白含量的方法分为标准定量、比色分析及紫外线吸收法,对以上三种方法实现精确定量的过程一一列举。希望与同行共同分享实践经验,实现对重组蛋白类药物蛋白含量的更精确测量,促进重组蛋白类药物完善进程。During quality control process of biotechnology drugs,accurate quantification of protein drugs is an important issue.from a macro perspective,the article divides methods of measuring protein content into standard quantification,colorimetric analysis and ultraviolet absorption method,and lists processes of above three methods to achieve precise quantification,to share practical experience with peers,and achieve more accurate measurement of protein content in recombinant protein drugs and promote improvement of recombinant protein drugs.

关 键 词：重组蛋白类药物 蛋白含量 测量方法 

分 类 号：R927.2[医药卫生—药学]