与结核相关的脂膜炎研究进展  

Tuberculosis-associated panniculitis

作　　者：颜韵灵 郑宝庆 王晓华 Yan Yunling;Zheng Baoqing;Wang Xiaohua(Dermatology Hospital of Southern Medical University,Guangzhou 510095,China)

机构地区：[1]南方医科大学皮肤病医院,广州510095

出　　处：《中华皮肤科杂志》2020年第11期944-947,共4页Chinese Journal of Dermatology

摘　　要：脂膜炎病因繁多而复杂,感染为重要病因之一,在欧美等结核低发区,以链球菌感染最为常见,但在结核高发地区如我国,结核杆菌感染是脂膜炎的重要因素,以Bazin硬红斑和结节性红斑最为常见。Bazin硬红斑与结核关系最为密切,常表现为下肢屈侧结节、斑块,可出现溃疡,病理表现为小叶性脂膜炎。结节性红斑可作为结核的早期症状出现,可作为结核的预测指标,常表现为双下肢伸侧红斑、结节,极少破溃,间隔性脂膜炎是其病理特征。Bazin硬红斑和结节性红斑的抗结核治疗常可取得理想效果。因此,明确结核分枝杆菌与脂膜炎的关系,在脂膜炎的治疗及预后方面,尤其在结核高发地区有着重要意义。The causes of panniculitis are various and complex,and infection is one of the important causes.Streptococcal infection is the most common cause in Europe and the United States with a low incidence of tuberculosis.In areas with a high incidence of tuberculosis such as China,Mycobacterium tuberculosis infection is an important cause of panniculitis,which commonly manifests as erythema induratum of Bazin and erythema nodosum.Erythema induratum of Bazinis is most closely related to tuberculosis,often clinically manifests as nodules,plaques and ulcers on the flexor aspect of the lower extremities,and pathologically manifests as lobular panniculitis.Erythema nodosum can be considered as an early symptom of tuberculosis,and serves as a predictive indicator of tuberculosis.It often manifests as erythema,nodules and few ulcers on the extensor aspect of both lower limbs,and is pathologically characterized by septal panniculitis.Antituberculosis treatment often yields favorable outcomes in patients with erythema induratum of Bazin or erythema nodosum.Therefore,clarifying the relationship between Mycobacterium tuberculosis and panniculitis is of great significance to the treatment and prognosis of panniculitis,especially in areas with a high incidence of tuberculosis.

关 键 词：脂膜炎 结核分枝杆菌 结节性红斑 Bazin硬红斑 

分 类 号：R529.4[医药卫生—内科学]