北京市丰台区阿尔茨海默病患病现状分析  

Prevalence of Alzheimer’s disease in Fengtai District,Beijing

作　　者：徐玉芝 柳欣[1] 尹志科[1] 邓永梅[1] XU Yu-zhi;LIU Xin;YIN Zhi-ke;DENG Yong-mei(Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院,北京100070

出　　处：《华南预防医学》2020年第5期502-505,共4页South China Journal of Preventive Medicine

摘　　要：目的了解北京市丰台区阿尔茨海默病(AD)患病现状,分析其影响因素,为制定健康管理政策提供科学依据。方法采用方便抽样方法抽取北京市丰台区≥60岁常住居民进行AD患病及相关因素调查,采用简易智能精神状态检查量表(MMSE)对调查对象进行初筛,阳性者由精神科医师按诊断标准确诊。采用描述流行病学方法进行分析,并采用单、多因素分析方法对AD患病影响因素进行分析。结果本研究调查丰台区≥60岁人群5901人,年龄60~92岁,以70~79岁为主,占39.3%,男女性别比为0.96∶1。检出AD者319例,患病率为5.41%。二分类Logistic回归分析结果显示,年龄增大(OR=2.284)、未婚/丧偶/离异(OR=2.487)、内向性格(OR=2.298)、过量饮酒(OR=12.820)、社会支持水平低(OR=1.514)、血脂异常(OR=2.512)均为老年AD的危险因素;有兴趣爱好(OR=0.299)、经常参加体育锻炼(OR=0.045)均为老年AD的保护因素。结论北京市丰台区老年人AD患病率较高,且随着年龄增大患病率升高,危险因素较多,应引起相关部门重视。Objective To understand the prevalence of Alzheimer’s disease(AD)in Fengtai District of Beijing and analyze its influencing factors,so as to provide scientific basis for formulating health management policies.Methods Convenience sampling method was used to select permanent residents≥60 years old in Fengtai District of Beijing for AD prevalence and related factors investigation,and the Simple Mental State Examination Scale(MMSE)was used to screen the elderly for AD.The positive cases were diagnosed by psychiatrists according to the diagnostic criteria.Descriptive epidemiological method was used for analysis,and univariate and multivariate logistic regressions were used to analyze the influencing factors of AD.Results A total of 5901 people aged 60-92 years old in Fengtai District were investigated,mainly 70-79 years old,accounting for 39.3%.The ratio of male to female was 0.96∶1.Three hundred and nineteen cases of AD were diagnosed,the prevalence rate was 5.41%.Binary logistic regression analysis showed that age increased(OR=2.284),unmarried/widowed/divorced(OR=2.487),introversion(OR=2.298),excessive drinking(OR=12.820),low level of social support(OR=1.514),dyslipidemia(OR=2.512)were the risk factors of AD in the elderly;interest(OR=0.299)and regular physical exercise(OR=0.045)were the protective factors.Conclusion The prevalence of AD in the elderly in Fengtai District of Beijing is relatively high,and with the increase of age,the prevalence increases.There are many risk factors of AD,and relevant departments should pay attention to it.

关 键 词：阿尔茨海默病 认知障碍 患病率 影响因素 

分 类 号：R195.4[医药卫生—卫生统计学]