基于有机小分子的“关-开”型铜(Ⅱ)离子荧光探针的应用现状  

Application Status of"Off-On"Fluorescent Probes for Cu(Ⅱ)ion Based on Small Molecules

作　　者：吴平[1] 任红[1] 韩丹丹[1] 高文秀[1] 芦菲[1] Wu Ping;Ren Hong;Han Dandan;Gao Wenxiu;Lu Fei(School of Chemistry and Pharmaceutical Engineering,Jilin Institute of Chemical Technology,Jilin 132022,China)

机构地区：[1]吉林化工学院化学与制药工程学院,吉林吉林132022

出　　处：《山东化工》2020年第20期39-41,共3页Shandong Chemical Industry

基　　金：吉林化工学院重大科技项目(2019014);吉林化工学院科学技术研究项目(2018030)。

摘　　要：基于有机小分子的铜(Ⅱ)离子荧光探针由于选择性好、灵敏度高、操作简单、重现性好且抗干扰性强,近年来引起了研究者的重视,在环境和生物检测领域的应用也日趋广泛。本文对“关-开”型铜离子荧光探针在矿泉水水质监测、游泳馆水样分析和生物细胞(如Vero、人张氏肝细胞、Hela、MCF-7和HepG2等)的荧光成像实例进行归纳,将对后续的荧光探针设计研发起到借鉴作用。Recently,the fluorescent probe for copper(Ⅱ)ions based on small organic molecules has attracted the attention of researchers due to its good selectivity,high sensitivity,simple operation,good reproducibility and strong anti-interference,and has been widely used in the field of environmental and biological detection.In this paper,the"off-on"type copper ion fluorescence probe is summarized in mineral water quality monitoring,swimming pool water sample analysis and fluorescence imaging of biological cells(such as Vero,human Zhang's liver cells,HeLa,MCF-7 and HepG2,etc.),which will play a reference role in the subsequent design and development of fluorescent probes.

关 键 词：铜离子 荧光探针 关-开 应用 

分 类 号：O655[理学—分析化学]