补阳还五汤加味内服联合穴位贴敷辅助治疗重型颅脑损伤后昏迷90例临床观察  

Clinical observation on oral administration of modified Buyang Huanwu Tang(补阳还五汤)combined with acupoint application in adjuvant treatment of 90 cases of coma after severe craniocerebral injury

作　　者：汝觅禄[1] 冯康[1] 王清平[1] 吴浩[1] 赵自育[1] 胥文德 RU Milu;FENG Kang;WANG Qingping;WU Hao;ZHAO Ziyu;XU Wende(Department of Neurosurgery,Tianshui Municipal the First People’s Hospital,Tianshui,Gansu,741000,China)

机构地区：[1]天水市第一人民医院神经外科,甘肃天水741000

出　　处：《甘肃中医药大学学报》2020年第5期56-60,共5页Journal of Gansu University of Chinese Medicine

摘　　要：目的观察补阳还五汤加味内服联合穴位贴敷辅助治疗重型颅脑损伤后昏迷的临床疗效。方法将179例重型颅脑损伤后昏迷患者采用随机数字表法分为对照组(89例)和治疗组(90例)。对照组给予西医常规治疗,治疗组在对照组治疗方法的的基础上给予补阳还五汤加味内服联合穴位贴敷治疗,10 d为1个疗程,共治疗3个疗程。1个月后随访,比较2组的临床疗效、平均昏迷时间、苏醒率,以及治疗前后格拉斯哥昏迷(GCS)评分、格拉斯哥预后(GOS)评分、Barthel指数。结果对照组总有效率为71.91%(64/89),治疗组为85.56%(77/90),2组比较差异有统计学意义(P<0.05)。治疗后2组GCS评分、GOS评分及Barthel指数均明显升高,与同组治疗前比较差异有统计学意义(P<0.05),且治疗组升高更明显,与对照组治疗后比较差异均有统计学意义(P<0.05)。治疗组苏醒率为78.89%(71/90),对照组为67.42%(60/89),2组比较差异有统计学意义(P<0.05)。治疗组平均昏迷时间为(7.02±1.24) d,对照组为(9.56±0.95) d,2组比较差异有统计学意义(P<0.05)。结论补阳还五汤加味内服联合穴位贴敷辅助治疗重型颅脑损伤后昏迷临床疗效显著,可明显提高患者GCS评分、GOS评分、Barthel指数及苏醒率,缩短昏迷时间,值得临床推广应用。Objective To observe the clinical efficacy of oral administration of modified Buyang Huanwu Tang(补阳还五汤) combined with acupoint application in adjuvant treatment of 90 cases of coma after severe craniocerebral injury. Methods Totally 179 cases of coma after severe craniocerebral injury were divided into control group with 89 cases and treatment group with 90 cases according to random number table method. The control group was given routine Western medicine treatment,on this basis,the treatment group was given oral administration of modified Buyang Huanwu Tang(补阳还五汤) combined with acupoint application. Ten days constituted 1 course of treatment,totally 3 courses of treatment. The patients were followed up 1 month later to compare the clinical efficacy,mean duration of coma,recovery rate,Glasgow coma scale(GCS) score,Glasgow outcome scale(GOS) score and Barthel index before and after treatment between the 2 groups. Results The total effective rate of the control group was 71.91%(64/89),that of the treatment group was 85. 56%(77/90),and the difference between the 2 groups was statistically significant(P<0.05). After treatment,GCS score,GOS score and Barthel index of the 2 groups all significantly increased,and the difference was statistically significant compared with the same group before treatment (P<0.05),moreover,the treatment group increased more significantly,and the difference was statistically significant compared with the control group after treatment(P<0.05). In the treatment group,the consciousness regaining rate was 78.89%(71/90),in the control group,that was 67. 42%(60/89),the difference between the two groups was statistically significant(P<0.05). The average coma duration of the treatment group was(7.02±1.24) days,and that of the control group was(9. 56 ± 0. 95) days,the difference between the 2 groups was statistically significant(P <0.05). Conclusion It has marked clinical efficacy to orally administer modified Buyang Huanwu Tang combined with acupoint application in adjuvant tr

关 键 词：重型颅脑损伤 昏迷 补阳还五汤 内服 穴位贴敷 格拉斯哥昏迷评分 格拉斯哥预后评分 Barthel指数 临床疗效 

分 类 号：R277.743.34[医药卫生—中医学]