儿童颈部淋巴结病变的临床分析  

Clinic analysis of cervical lymph node lesions in children

作　　者：娄凡[1] 张铁松[1] 明澄 马静[1] 王美兰[1] 曾文娟[1] LOU Fan;ZHANG Tiesong;MING Cheng;MA Jing;WANG Meilan;ZENG Wenjuan(Department of Otolaryngology Head and Neck Surgery,Kunming Children's Hospital,Head and Neck Disease Diagnosis and Treatment Center,Kunming,650228,China)

机构地区：[1]昆明市儿童医院(昆明医科大学附属儿童医院)耳鼻咽喉头颈外科,昆明市儿童医院头颈疾病诊治中心,昆明650228

出　　处：《临床耳鼻咽喉头颈外科杂志》2020年第10期928-931,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨不同病理类型的儿童颈部淋巴结病变的临床特征,为疾病的早期诊断提供帮助。方法:收集经淋巴结活检确诊的73例颈部淋巴结病变的患儿资料,分析不同病理类型的颈部淋巴结病变患儿的性别构成、年龄分布、淋巴结特征及临床表现。结果:73例颈部淋巴结病变患儿中,良性疾病组男性发病小于女性,恶性疾病组男性发病大于女性,两组性别构成差异均有统计学意义(P<0.05)。良性疾病组在学龄期占比最大(27.4%),恶性疾病组在学龄前期(21.9%)和学龄期(20.5%)占比大,两组均在婴幼儿期和青春期占比较小,两组组内年龄分布差异有统计学意义(P<0.01)。各病理类型中,73例患儿以淋巴结炎性反应性增生占比最大,为35.6%(26/73),主要在学龄期发病;其次为霍奇金淋巴瘤,占比20.5%(15/73),主要在学龄前期和学龄期发病。恶性疾病组的淋巴结平均最大横径值大于良性疾病组(P<0.05)。良性疾病组的淋巴结主要分布于Ⅰ、Ⅱ、Ⅲ区,恶性疾病组的淋巴结主要分布于Ⅱ、Ⅲ、Ⅳ、Ⅴ区,两组间肿大淋巴结的分布差异有统计学意义(P<0.01)。结论:不同病理类型的儿童颈部淋巴结病变在性别构成、年龄分布、淋巴结大小及分布上存在差异,儿童颈部淋巴结病变有其自身特点。Objective:Explore the clinical features of cervical lymph node lesions in children with different pathological types,and provide help for the early diagnosis of the disease.Method:The data of 73children with cervical lymph node disease diagnosed by lymph node biopsy were collected,and the gender composition,age distribution,lymph node characteristics and clinical manifestations of children with different pathological types were analyzed.Result:Among the 73children with cervical lymph node disease,the incidence of male patients in the benign disease group was less than that of female ones,and the incidence of male patients in the malignant disease group was greater than that of female ones,the difference in gender composition between the two groups was statistically significant(P<0.05).The benign disease group had the largest proportion in the school-age period(27.4%),and the malignant disease group had a larger proportion in the preschool period(21.9%)and school-age period(20.5%),both groups had a relatively smaller proportion in the infant and adolescent period,the difference in age distribution within the group was statistically significant(P<0.01).Among the various pathological types,the proportion of 73children with lymph node inflammatory reactive hyperplasia was the largest,35.6%(26/73),and was mainly at school age;the second was Hodgkin's lymphoma,accounting for 20.5%(15/73),mainly in the preschool and school age.The average maximum transverse diameter of lymph nodes in the malignant disease group was greater than that in the benign disease group(P<0.05).The lymph nodes in the benign disease group were mainly distributed in areasⅠ,Ⅱ,andⅢ,and the lymph nodes in the malignant disease group were mainly distributed in areasⅡ,Ⅲ,Ⅳ,andⅤ,there was a statistically significant difference in the distribution of enlarged lymph nodes between the two groups(P<0.01).Conclusion:Different pathological types of cervical lymph node lesions in children are different in gender composition,age distribution,lymph n

关 键 词：儿童 颈部 淋巴结病 病理学 

分 类 号：R726.53[医药卫生—儿科]