钬激光前列腺剜除术治疗良性前列腺增生的疗效  

Efficacy of holmium laser enucleation of prostate in treating patients with benign prostatic hyperplasia

作　　者：吴浩然 王旭刚[1] 张亮 史红雷[1] 吕忠[1] WU Haoran;WANG Xugang;ZHANG Liang(Department of Urology,Wujin People’s Hospital of Changzhou,Changzhou213017,CHINA)

机构地区：[1]常州市武进人民医院泌尿外科,江苏213017

出　　处：《江苏医药》2020年第10期1004-1007,共4页Jiangsu Medical Journal

基　　金：常州市武进区科委项目(WS201707)。

摘　　要：目的观察钬激光前列腺剜除术(HoLEP)治疗良性前列腺增生(BPH)的疗效。方法92例BPH患者分为观察组和对照组,每组46例。观察组行HoLEP,对照组行前列腺等离子电切术(PKRP)。观察两组患者围手术期指标及术后并发症发生情况。记录两组术前和术后3、6个月最大尿流率(Qmax)和残余尿量(PVR),评估国际前列腺症状评分(IPSS评分)和生活质量评分(QOL评分)。结果与对照组比较,观察组手术时间长,前列腺切除重量重,但术中出血量少,导管留置时间和住院时间短(P<0.05)。观察组术后并发症发生率低于对照组(8.7%vs.26.1%)(P<0.05)。两组术后Qmax和PVR均优于术前(P<0.05),且观察组术后Qmax高于对照组,而PVR低于对照组(P<0.05)。两组术后IPSS评分和QOL评分均低于术前(P<0.05),且观察组术后IPSS和QOL评分均低于对照组(P<0.05)。结论与PKRP比较,HoLEP可减少BPH患者术中出血,提高Qmax,降低PVR,减少术后并发症发生,缩短住院时间。Objective To observe the efficacy of holmiumb laser enucleation of the prostate(HoLEP)in treating the patients with benign prostatic hyperplasia(BPH).Methods Ninety-two patients with BPH were divided into two groups with 46 cases each.The patients in group A were treated with HoLEP and those in group B were treated with plasmakinetic resection of prostate(PKRP).The perioperative indicators and postoperative complications of the two groups were observed.The maximum urinary flow rate(Qmax)and post-void residual urine volume(PVR)were recorded and the international prostate symptom score(IPSS)and quality of life(QOL)score were evaluated before and in the 3rd and 6th month after operation.Results Compared with group B,group A had longer operation time,more weight of the prostate resected,less intraoperative blood loss,shorter time for catheter indwelling and hospital stay(P<0.05).The incidence of postoperative complications in group A was lower than that in group B(8.7%vs.26.1%)(P<0.05).The Qmax and PVR in two groups after operation were better than those before(P<0.05).Compared with group B after operation,the Qmax was higher and the PVR was less in group A(P<0.05).The scores of IPSS and QOL in two groups after operation were better than those before(P<0.05),which after operation were better in group A than those in group B(P<0.05).Conclusion Comared to PKRP in the patients with BPH,HoLEP has the advantages of reducing intraoperative bleeding,increasing Qmax,decreasing PVR,decreasing complications,and shortening hospital stay.

关 键 词：良性前列腺增生 钬激光前列腺剜除术 

分 类 号：R697[医药卫生—泌尿科学]