磁共振技术联合弥散张量成像在老年颅脑损伤患者病情评估中的应用  

The application of MRI combined with diffusion tensor imaging in disease evaluation of elderly patients with craniocerebral injury

作　　者：褚爱鹏[1] Chu Aipeng(Department of Radiology,Shangqiu First People's Hospital,Shangqiu 476100,China)

机构地区：[1]商丘市第一人民医院放射科,476100

出　　处：《中华老年医学杂志》2020年第11期1274-1278,共5页Chinese Journal of Geriatrics

摘　　要：目的观察磁共振技术(MRI)联合弥散张量成像(DTI)用于评估老年颅脑损伤患者病情的价值。方法回顾性分析,纳入商丘市第一人民医院2017年1月至2019年11月80例老年颅脑损伤患者,参照相关标准并结合格拉斯哥评分(GCS)评价颅脑损伤程度,将轻度患者纳入轻度组(33例)、其余纳入中重度组(47例);纳入同期健康老年人40例作为对照组。全部纳入对象在入院当天接受头颅MRI检查,记录受检者基线资料,观察不同程度颅脑损伤患者MRI检查各序列表现及出血灶检出数,分析MRI联合DTI评估患者病情的价值。结果各组基线资料比较差异均无统计学意义(均P<0.05);轻度组患者额叶、颛叶、耕月氐体、基底节、丘脑、脑干、小脑出血灶检出数量均少于中重度组,差异有统计学意义(t=21.479、19.270、48.901、23.003、10.112、16.108、13.934,均P<0.001);3组除脑桥左右侧FA值外(F=1.988、1.732,P=0.142、0.181),额叶白质、额叶白质、脐月氐体、脑桥、内囊左右侧FA值、ADC值比较差异均有统计学意义(Ffa=93.570、449.338、58.371.126.061.35.422.15.002、140.938、187.958,FADC=97.790、59.383、58.661、60.141、31.042、40.147、57.696、58.011、30.962、31.741,均P<0.001),且以中重度损伤组FA.ADC值最低,后由低至高依次为轻度损伤组、对照组。结论MRI联合DTI扫描能够全面且清晰显示老年颅脑损伤患者的颅内病变情况,MRI检出出血灶数目越多、DTI检查显示观察区FA值或ADC值越低,提示患者损伤程度越严重。Objective To assess the value of magnetic resonance imaging(MRI)combined with diffusion tensor imaging(DTI)in disease evaluation of elderly patients with craniocerebral injury.Methods A total of 80 elderly patients with craniocerebral injury from January 2017 to November 2019 in Shangqiu First People's Hospital were included and retrospectively analyzed.Based on the degree of craniocerebral injury assessed using relevant standards combined with the Glasgow score(GCS),patients with mild injury were included in the mild group(n=33),and the rest were included in the moderate and severe group(n=47).Another 40 healthy elderly persons from the same period were enrolled in the control group.All subj ects underwent head MRI on the day of admission.Baseline data were recorded.The performance of each sequence of MRI examination and the number of detected bleeding lesions in patients were recorded.The value of MRI combined with DTI on craniocerebral inj ury evaluation was analyzed.Results There was no significant difference in baseline data between the groups(all P<0.05).The number of bleeding lesions in the frontal lobe,temporal lobe,corpus callosum,basal ganglia,thalamus,brainstem and cerebellum was lower in the mild group than in the moderate and severe group(t=21.479,19.270,48.901,23.003,10.112,16.108 and 13.934,all P<0.001).The FA and ADC values of the frontal lobe white matter,temporal lobe white matter,corpus callosum,pons,left and right sides of the internal capsule had significant differences between the three groups(FFA=93.570,449.338,58.371,126.061,35.422,15.002,140.938 and 187.958,FADC=97.790,59.383,58.661,60.141,31.042,40.147,57.696,5&011,30.962 and 31.741,all P<0.001),except those of the left and right sides of the pons(F=1.988 and 1.732,P=0.142 and 0.181),and the moderate and severe group had the lowest FA and ADC values,followed the mild group and the control group.Conclusions MRI combined with DTI scan can comprehensively and clearly show intracranial lesions in elderly patients with craniocerebral injury.T

关 键 词：颅脑损伤 病情评估 磁共振成像 弥散 

分 类 号：R651.15[医药卫生—外科学] R445.2[医药卫生—临床医学]