肺NUT癌的CT表现  

CT findings of the pulmonary NUT carcinoma

作　　者：张浩[1] 方旭[1] 卢明智[2] 王洋[1] 王铁功[1] 刘芳[1] 邵成伟[1] ZHANG Hao;FANG Xu;LU Ming-zhi(Department of Radiology,Changhai Hospital,the Second Military Medical University,Shanghai 200433,China)

机构地区：[1]第二军医大学附属长海医院影像医学科,上海200433 [2]第二军医大学附属长海医院放疗科,上海200433

出　　处：《放射学实践》2020年第11期1415-1418,共4页Radiologic Practice

摘　　要：目的:探讨肺NUT癌的CT表现,以提高对该病的认识。方法:回顾性分析经病理确诊的7例肺NUT癌患者的临床、病理及影像资料。结果:肿块位于右肺5例,左肺2例。7例患者肺内肿块均为分叶状,最大径3~15 cm,平均最大径为7.6 cm;CT平扫密度不均匀,3例行增强扫描肿块呈中度强化。6例发生转移,其中纵隔或肺门淋巴结转移4例,骨转移3例,肾上腺转移、肝转移、脑转移均为2例。肿瘤细胞多排列成片状及不规则巢状,多数细胞未分化,局部呈鳞状细胞分化。7例免疫组化NUT均为阳性,NUT基因断裂重组检测均为阳性。结论:肺NUT癌多见于右肺,表现为分叶状肿块,体积较大,密度不均匀,增强扫描呈不均匀中度强化,远处转移多见。Objective:To investigate the CT findings of the pulmonary NUT carcinoma and to improve the diagnostic accuracy.Methods:The clinical,imaging and pathological data of 7 patients with pulmonary NUT carcinoma confirmed by pathology were retrospectively analyzed.Results:Mass was located in the right lung in 5 cases and 2 masses in the left lung.All the masses were of lobulated margin.The maximum diameter of the masses ranged from 3cm to 15cm(mean 7.6cm).The density of 7 masses was uneven.3 cases undergoing enhanced CT scan showed moderate enhancement.Distant metastases occurred in 6 patients,including 4 in hilar or mediastinal lymph nodes,3 in bones,2 in adrenal glands,2 in liver,and 2 in brain.The tumor cells were mostly arranged in shapes of sheet and irregular nest and poorly differentiated,with focal differentiation to squamous cells.7 cases were positive for NUT immunohistochemical staining and NUT gene recombination.Conclusion:Characteristic findings of the location,boundary and degree of enhancement in pulmonary NUT carcinoma can be assessed.All the lesions are lobulated with well-defined margin and moderate enhancement.Most lesions are located in the right lung and present as a large mass.The pulmonary NUT carcinoma is prone to distant metastasis.

关 键 词：NUT癌 肺肿瘤 体层摄影术 X线计算机 

分 类 号：R814.42[医药卫生—影像医学与核医学] R734.2[医药卫生—放射医学]