阴道微生态与HIV感染的研究进展  

Advances in vaginal microecology and HIV infection

作　　者：李梅正 任莉[2] LI Meizheng;REN Li(The Third People's Hospital Of Kunming,Kunming 650200,Yunnan,China;The First People's Hospital Of Yunnan Province,Kunming 650118,Yunnan)

机构地区：[1]昆明市第三人民医院,昆明650200 [2]云南省第一人民医院,昆明650118

出　　处：《中国艾滋病性病》2020年第10期1136-1139,共4页Chinese Journal of Aids & STD

摘　　要：现阶段,全球艾滋病病毒(HIV)感染者数目庞大,我国近几年的感染率仍在上升,特别是性传播方式感染HIV比例增加。HIV女性感染者的阴道微生态多样性、性传播疾病的共感染率均较HIV阴性女性发生率高,其阴道微生态的改变也增加了HIV的感染风险。多项研究表明:细菌性阴道病(BV)患者HIV的感染风险增加,且HIV感染者阴道内人乳头瘤病毒、滴虫、衣原体、梅毒等其他性传播疾病检出率增加。因此,有效治疗BV及恢复阴道微生态平稳,可以明显降低性传播疾病的发生,包括HIV感染。本文总结了国内外探讨HIV感染与阴道微生态之间关系的多项研究,期望阐明保持阴道微生态平衡对降低HIV感染的重要作用。As it is known,the number of people infected with HIV globally is 37.9 million,and the infection rate in China is still rising in recent years,particularly the proportion of sexually transmitted HIV infection.The vagina microecological diversity and the co-infection rate of sexually transmitted diseases among HIV-infected women are higher than those of HIV negative women and their vaginal microecological changes also increase the risk of HIV infection.Many studies have showed that people with bacterial vaginosis(BV)have increased risk of HIV infection.In addition,the detection rates of human papillomavirus,trichomonas,chlamydia,treponema pallidum and other sexually transmitted diseases in the vagina of HIV-infected patients have increased.So,effective treatment of BV and restoration of vaginal microecology can significantly reduce the incidence of sexually transmitted diseases,including HIV infection.This paper summarizes a number of studies on the relationship between HIV infection and vaginal microecology at home and abroad,with the hope to clarify the important role of maintaining vaginal microecology balance in reducing HIV infection.

关 键 词：艾滋病病毒 阴道微生态 性传播疾病 多样性 

分 类 号：R512.91[医药卫生—内科学] R373.9[医药卫生—临床医学]