碘普罗胺注射液外渗致严重皮下血肿和感染  

Severe subcutaneous hematoma and infection caused by extravasation of iopromide injection

作　　者：马素文[1,2] 孙峥 邵越英[3] 杜祥颖 卢洁[1,2] Ma Suwen;Sun Zheng;Shao Yueying;Du Xiangying;Lu Jie(Department of Radiology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics,Beijing 100053,China;Department of Education,Xuanwu Hospital,Capital Medical University,Beijing,100053,China)

机构地区：[1]首都医科大学宣武医院放射科,北京100053 [2]磁共振成像脑信息学北京市重点实验室,北京100053 [3]首都医科大学宣武医院教育处,北京100053

出　　处：《药物不良反应杂志》2020年第10期603-605,共3页Adverse Drug Reactions Journal

基　　金：北京市医院管理局"登峰"计划专项经费资助(DFL20180802)。

摘　　要：1例69岁女性糖尿病患者因急性脑梗死行头部血管造影术。术前在高压注射器静脉注射碘普罗胺-370时发生右手注射部位造影剂外渗,造成严重皮下血肿、组织坏死和感染,外渗创面最大至6.0 cm×7.0 cm。给予50%硫酸镁+地塞米松冷局部湿敷,每日清创换药,外敷水凝胶、亲水纤维银、水胶体敷料等治疗,外渗后第14天创面坏死组织逐渐脱落,伤口开始愈合;外渗后第35天创面完全愈合。A 69-year-old female patient with diabetes mellitus was scheduled to undergo angiography of head because of acute cerebral infarction.When iopromide injection-370 was injected intravenously with a high-pressure syringe before operation,the contrast medium extravasated at the injection site of her right hand,resulting in severe subcutaneous hematoma,tissue necrosis,and infection.The maximum area of extravasation wound extended to 6.0 cm×7.0 cm.Therapies such as local wet compress with cold 50%magnesium sulfate and dexamethasone,daily debridement and dressing change,and external application of hydrogel,silver containing hydrophilic foam,and hydrocolloid were given.On day 14 after extravasation,the necrotic tissue of the wound gradually fell off and the wound began to heal.Then the wound healed on day 35 after extravasation.

关 键 词：造影剂 诊断和治疗物质外渗 血肿 感染 护理 

分 类 号：R969[医药卫生—药理学]