526例丹毒患者复发的相关危险因素分析  

Analysis of Risk Factors Associated with Recurrence in 526 Patients with Erysipelas

作　　者：赵志国[1] 栾文康 马朝东[1] 张宇[1] 张彩萍[1] 尹雪锋[1] 丁克云[1] ZHAO Zhiguo;LUAN Wenkang;MA Chaodong;ZHANG Yu;ZHANG Caiping;YING Xuefeng;DING Keyun(Department of Dermatology,the Affiliated People's Hospital of Jiangsu University,Zhenjiang 212002,Jiangsu,China)

机构地区：[1]江苏大学附属人民医院皮肤美容科,江苏镇江212002

出　　处：《贵州医科大学学报》2020年第11期1328-1332,共5页Journal of Guizhou Medical University

基　　金：国家自然科学基金项目(81802726)。

摘　　要：目的:探讨影响丹毒患者复发的相关危险因素。方法:选择诊断明确的丹毒住院患者526例,根据出院后1~5年的复发情况分为复发组(n=152)与初发组(n=372),比较2组患者住院期间的一般和既往可能的相关危险因素病史、血压、体温、血糖、血常规、血白细胞计数(WBC)、C反应蛋白(CRP)及其他相关检查结果,随访和比较2组患者出院后1~5年病情(是否复发、复发时间及复发部位)、维持治疗方案、维持治疗时间及病程描述等信息;采用Logistic回归模型对以上各相关危险因素进行分析。结果:526例患者中发生复发性丹毒152例,复发率为28.9%;2组患者的发病时间、部位、CRP升高、WBC升高、标准治疗、住院时间、慢性淋巴水肿、行淋巴结清扫、痛风、外伤及非标准治疗等危险因素比较,差异有统计学意义(P<0.05或P<0.01);Logistic多因素分析显示,慢性淋巴水肿(OR=3.593,P<0.05)、淋巴结清扫(OR=13.102,P<0.05)及患侧外伤(OR=0.197,P<0.05)为丹毒复发的危险因素。结论:慢性淋巴水肿、肿瘤患者淋巴结清扫及患侧外伤是丹毒复发的最主要危险因素。Objective:To explore the related risk factors of erysipelas recurrence and to provide the basis for the correct formulation of treatment plan.Methods:526 patients with erysipelas were selected and divided into recurrence group(n=152)and initial group(n=372)according to the recurrence situation in 1~5 years after discharge.The general and possible risk factors,blood pressure,body temperature,blood glucose,blood routine,white blood cell(WBC),C-reactive protein(CRP)and other related examination results were compared between the two groups during hospitalization.All patients were followed up and compared with the situations(including recurrence possibility,recurrence time and recurrence site),maintenance treatment plan,maintenance treatment time and course description for 1 to 5 years after discharge.Logistic regression model was used to analyze the above risk factors.Results:There were 152 cases of recurrent erysipelas in 526 cases,the recurrence rate was 28.9%;there were statistically significant differences in the risk factors of onset time,location,elevated CRP and WBC,standard treatment,hospitalization days,chronic lymphedema,lymph node dissection,gout,trauma and non-standard treatment between the two groups(P<0.05).Logistic multivariate analysis showed that chronic lymphedema(OR=3.593,P<0.05),lymph node dissection(OR=13.102,P<0.05)and trauma(OR=0.197,P<0.05)were the risk factors of erysipelas recurrence.Conclusion:Chronic lymphedema,lymph node dissection,and trauma are the main risk factors for erysipelas recurrence.

关 键 词：丹毒 复发 危险因素 淋巴水肿 皮肤感染 治疗 预防 

分 类 号：R753.[医药卫生—皮肤病学与性病学]