基于ESIPT机理香豆素荧光化合物的合成和光学性质  

Synthesis and Optical Properties of Coumarin Fluorescent Compound Based on ESIPT Mechanism

作　　者：许磊 姜静静 陈宇 李龙春 XU Lei;JIANG Jing-jing;CHEN Yu;LI Long-chun(Department of Applied Chemistry,School of Science,Anhui Agricultural University,Hefei 230036,China)

机构地区：[1]安徽农业大学理学院应用化学系,安徽合肥230036

出　　处：《合成化学》2020年第11期994-997,1002,共5页Chinese Journal of Synthetic Chemistry

基　　金：安徽省大学生创业训练计划项目(201810364079,201810364069);安徽省自然科学基金资助项目(2008085MB41)。

摘　　要：以3-碘苯酚为原料,经过甲酰化反应、Knoevenagel缩合反应、Sonogashira偶联和还原反应得到以香豆素为母体的目标化合物7-(甲氧基苯乙炔基)香豆素-3-甲醇(5)。化合物5的结构经过1H NMR,13C NMR和MS(ESI)分析表征确认。并对化合物5的光学性质进行了研究,结果表明:化合物5具有典型的ESIPT发光机理,可以构建比率计量型双光子荧光探针。We have designed and synthesized a novel target compound,7-(4-methoxyphenylethynyl)coumarin-3-methanol(5),through formylation,Knoevenagel condensation reaction,Sonogashira couple reaction and reduction reaction using 3-lodophenol as the raw material.The structure was characterized by 1H NMR,13C NMR and MS(ESI).Moreover,the optical properties of the compound 5 were investigated.The results indicate that 5 has a typical Excited-state Intramolecular Proton Transfer(ESIPT)process.Meanwhile,we can construct a novel ratiometric two-photon fluorescent probe.

关 键 词：香豆素 光学性质 ESIPT机理 比率计量 合成 

分 类 号：O625.15[理学—有机化学]