猪DKK2基因的多态性与母猪产仔数性状的关联分析  

Association analysis of polymorphism of pig DKK2 gene and sow litter size traits

作　　者：周佳伟 乔木[1] 吴俊静[1] 王孝忠 刘贵生[1] 梅书棋[1] 彭先文[1] ZHOU Jia-wei;QIAO Mu;WU Jun-jing;WANG Xiao-zhong;LIU Gui-sheng;MEI Shu-qi;PENG Xian-wen(Hubei Key Laboratory of Animal Embryo and Molecular Breeding/Institute of Animal Science and Veterinary Medicine,Hubei Academy of Agricultural Science,Wuhan 430064,China;Animal Disease Prevention and Control Center of Yichang City,Yichang 443000,Hubei,China)

机构地区：[1]湖北省农业科学院畜牧兽医研究所/动物胚胎工程及分子育种湖北省重点实验室,武汉430064 [2]湖北省宜昌市动物疫病预防控制中心,湖北宜昌443000

出　　处：《湖北农业科学》2020年第20期138-140,共3页Hubei Agricultural Sciences

摘　　要：母猪的繁殖性状是猪重要经济性状之一,但由于其遗传力低,导致母猪繁殖性状常规选择进展缓慢。通过SANGER测序的方法检测DKK2基因内SNP位点,并与产仔数性状进行关联分析。结果表明,在DKK2基因第二内含子存在一个新SNP位点,根据SNP命名方法将其命名为8:g.114967878A>G,且该SNP位点与产活仔数性状显著相关。猪DKK2基因的新SNP位点8:g.114967878A>G对猪的产活仔数性状存在潜在的调控作用。The reproductive trait of sows is one of the important economic traits of pigs,but due to its low heritability,the conventional selection of reproductive traits of sows has been slow.SANGER sequencing was used to detect the SNP locus in the DKK2,and the cor⁃relation analysis was performed with the litter size traits.The results showed that there was a new SNP locus in the second intron of the DKK2,which was named 8:g.114967878A>G,and the SNP locus was significantly related to the number of live births.The new SNP site 8:g.114967878A>G of DKK2 in pigs has effect on the number of live births.

关 键 词：猪 DKK2 SNP 产仔数 

分 类 号：S828[农业科学—畜牧学] Q343.15[农业科学—畜牧兽医]