冠心病患者中心动脉血压与肱动脉血压的差值及影响因素  

Difference between central arterial blood pressure and brachial blood pressure and influencing factors in patients with coronary artery disease

作　　者：罗迪[1] 王小飞[1] 王蕾[1] Luo Di;Wang Xiaofei;Wang Lei(International Medical Centre,Tianjin First Central Hospital,Tianjin 300192,China)

机构地区：[1]天津市第一中心医院国际诊疗中心,天津300192

出　　处：《临床荟萃》2020年第12期1089-1092,共4页Clinical Focus

基　　金：天津市第一中心医院春风计划(院CF201821)——老年冠心病患者主动脉根部血压与肱动脉血压的相关性及其影响因素中国临床试验注册中心注册号:ChiCTR-ROC-17013606。

摘　　要：目的分析肱动脉血压与中心动脉血压的差值,评价中老年冠心病患者外周与中心动脉血压差异的影响因素。方法选取2018年5月-2019年4月于我科因心血管疾病入院并接受冠状动脉造影患者,根据近1月内有无出现心功能不全临床症状,将入选患者分为心功能不全组即实验组(51例)和对照组(66例),记录两组患者性别、年龄、体质量指数(BMI)、左心室射血分数(LVEF)、B型利钠肽(NT-proBNP)、肌酐、糖化血红蛋白及血脂情况,冠状动脉造影术中记录中心动脉收缩压cSBP、中心动脉舒张压cDBP,同时测量肱动脉SBP、DBP值,应用Genaini积分法评估冠状动脉病变程度及范围。结果实验组LVEF小于对照组(P<0.05),两组cSBP,cDBP、△SBP(△SBP=SBP-cSBP),△DBP(△DBP=DBP-cDBP)、Genaini积分与对照组相比差异均有统计学意义(P<0.05)。冠状动脉Genaini积分为△BP<10的危险因素(P<0.01,OR=28.836)。结论监测中心动脉-肱动脉血压差值可能为评估冠状动脉血管病变程度提供参考。Objective To analyze the difference between central arterial blood pressure and brachial blood pressure,and to evaluate the influencing factors of the difference between peripheral blood pressure and central arterial blood pressure in middle-aged and elderly patients with coronary artery disease.Methods Patients with cardiovascular disease and undergoing coronary arteriography were selected from May,2018 to April,2019.According to whether there were clinical symptoms of cardiac insufficiency,the patients were divided into experimental group(51 cases)and control group(66 cases).The data of patients in two groups were recorded,including gender,age,body mass index(BMI),LVEF,NT-proBNP,creatinine,glycosylated hemoglobin and blood lipids.The cSBP,cDBP were recorded in the period of coronary arteriography,and SBP and DBP value of brachial were measured at the same time.Genaini integral method was used to evaluate the degree of coronary artery lesions and range.Results The LVEF value in experimental group was lower than that in control group(P<0.05).There were significant differences in cSBP,cDBP,△SBP(△SBP=SBP-cSBP),△DBP(△DBP=DBP-cDBP)and Genaini integral between two groups(P<0.05).Genaini integral was a risk factor of△BP<10(P<0.01,OR=28.836).Conclusion Monitoring of difference between central artery and brachial artery blood pressure may provide reference for evaluating the degree of coronary artery lesions.

关 键 词：高血压 冠状动脉病 中心动脉压 心脏功能试验 老年人 

分 类 号：R541.4[医药卫生—心血管疾病]