急性心肌梗死患者残余胆固醇及血常规参数变化的意义  

Changes in Residual Cholesterol and Routine Blood Parameters in Patient with Acute Myocardial Infarction

作　　者：巨名飞[1] 刘超[1] 于健[1] 赵艳军[1] 刘环亚[1] 刘艳平 王智昊[2] Ju Mingfei;Liu Chao;Yu Jian;Zhao Yanjun;Liu Huanya;Liu Yanping;Wang Zhihao(Department of Emergency Medicine,the affiliated Hospital of Chengde Medical College,Chengde 067000,China;Department of Geriatrics,the First hospital of Jilin University,Changchun 130021,China)

机构地区：[1]承德医学院附属医院急诊医学科,承德067000 [2]吉林大学第一医院老年病科,长春130021

出　　处：《国际老年医学杂志》2020年第6期364-366,共3页International Journal of Geriatrics

基　　金：吉林省自然科学基金(省联合基金白求恩医学专项)(20200201319JC);承德市科学技术研究与发展计划项目(201801A026)。

摘　　要：目的通过分析残余胆固醇(RC)及血常规参数在急性心肌梗死(AMI)患者中的变化,探讨AMI诊断与残余胆固醇及血常规参数等指标的相关性。方法选取2017年1月~2018年2月于承德医学院附属医院心内科住院诊断为AMI的患者196例为AMI组,选取同期体检科健康人群180例为对照组。比较两组间血脂及血常规参数水平的差异。结果 AMI组白细胞计数、中性粒细胞比率(NEUT)、血小板计数(PLT)、血小板宽度(PDW)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDLC)、RC,高血压及吸烟患者比例均高于对照组,差异均有统计学意义(P <0.05)。Logistic分析显示,AMI的独立危险因素有RC、LDL-C、PDW、PLT、TC、高血压及吸烟。RC与AMI发病率相关性最高。结论 RC、LDL-C、PDW、PLT、TC、AMI、高血压及吸烟存在相关性,RC对于AMI的发病有一定预测诊断价值。Objective To analyze the changes of residual cholesterol(RC)and routine blood parameters in patients with acute myocardial infarction(AMI),and to explore the correlation between AMI diagnosis and residual cholesterol,routine blood parameters.Methods From January 2017 to February 2018,196 patients with AMI diagnosed in the Affiliated Hospital of Chengde Medical College were selected as AMI group,and 180 healthy people in the same period were selected as control group.The levels of blood lipid and routine blood parameters between the two groups were compared.Results White blood cell count,neutrophil ratio(NEUT),platelet count(PLT),platelet width(PDW),the levels of total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),residual cholesterol(RC),the rate of people with hypertension and smoking history in AMI group were higher than those in control group(P<0.05).Logistic analysis showed that RC,LDL-C,PDW,PLT,TC,hypertension and smoking were the independent risk factors of AMI.Residual cholesterol was the most relevant to AMI incidence.Conclusion RC,LDL-C,PDW,PLT,TC,hypertension and smoking are correlated with AMI.RC might have the predictive diagnostic value for AMI.

关 键 词：残余胆固醇 急性心肌梗死 血脂 血常规 

分 类 号：R542.22[医药卫生—心血管疾病] R446.11[医药卫生—内科学]