替代物治疗盆底功能障碍性疾病的应用前景  

Application prospect in substitute for the treatment of pelvic floor dysfunction

作　　者：刘娟[1] 陈硕臻 LIU Juan;CHEN Shuo-zhen(The Third Affiliated Hosptial of Guangzhou Medical University,Research Institute of Gynecology and Obstetrics,Guangzhou 510150,China)

机构地区：[1]广州医科大学附属第三医院,广州市妇产科研究所,广东广州510150

出　　处：《中国实用妇科与产科杂志》2020年第10期927-928,929,930,共4页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家自然科学基金(8167060599);广东省科技计划项目(20140211)。

摘　　要：目前用于治疗盆底功能障碍性疾病(pelvic floor dysfunction,PFD)的替代物主要是指网片,根据材料分为人工合成网片、生物补片和组织工程学网片。中重度盆腔器官脱垂(pelvic organ prolapse,POP)和压力性尿失禁(stress urinary incontinence,SUI)使用网片的手术方法包括经阴道植入网片(transvaginal mesh implantation,TVM)手术、阴道骶骨固定术(sacrocolpopexy,SC)和无张力尿道中段吊带术(mid-urethralslings,MUS),网片的并发症使网片手术陷入争论。文章通过论述网片手术现状、网片材质、手术操作的改进、生物力学的发展和监管随访机制的建立,探讨网片在PFD中的应用。The substitute for the treatment of pelvic floor dysfunction mainly refer to "mesh",which can be divided into synthetic mesh,biological mesh and tissue-engineered mesh according to the materials.Surgical managements with mesh for moderate and severe pelvic organ prolapse(POP) and stress urinary incontinence(SUI) include transvaginal mesh(TVM),sacrocolpopexy(SC),and mid-urethralslings(MUS).Complications related to mesh have caused controversy in the application of the mesh.The application of mesh in PFD is discussed based on the current status of mesh operation,the improvement in mesh material and operation,biomechanics development and the establishment of supervision and follow-up mechanism.

关 键 词：盆底功能障碍性疾病 网片 生物工程技术 应用前景 

分 类 号：R711.2[医药卫生—妇产科学]