3071例成人新登记涂阳肺结核患者治疗结局分析  

Analysis of treatment outcome of 3071 newly registered smear positive tuberculosis patients in adults

作　　者：龚新记[1] 文进[2] 李月华 王晶 吴刚 胡昕[1] 王希江[5] GONG Xinji;WEN Jing;LI Yuehua;WANG Jing;WU Gang;HU Xin;WANG Xijiang(Department of Respiratory,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054;Department of Critical Care Medicine,the Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830028;Department of Tuberculosis,Wuhan Pulmonary Hospital,Wuhan 430000;State Key Laboratory of Pathogenesis,Pre-vention,and Treatment of Diseases Highly Prevalent in Central Asia,Urumqi 830054;The Center for Disease Control and Prevention of Xinjiang Uygur Autonomous Region,Urumqi 830000,China)

机构地区：[1]新疆医科大学第一附属医院呼吸科,乌鲁木齐830054 [2]新疆医科大学第二附属医院重症医学科,乌鲁木齐830028 [3]武汉市肺科医院结核病科,武汉430000 [4]省部共建中亚高发病成因与防治国家重点实验室,乌鲁木齐830054 [5]新疆维吾尔自治区疾病预防控制中心结核病防治中心,乌鲁木齐830000

出　　处：《新疆医科大学学报》2020年第11期1514-1517,共4页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区重大科技专项(2017A03006-2)。

摘　　要：目的评估新登记涂阳结核患者的治疗结局,同时确定治疗不成功的相关影响因素。方法采用回顾性队列研究的方法,纳入3071例成人涂阳结核患者,登记个人信息,定期复诊随访,并接受抗结核治疗,追踪患者治疗结局。建立Logistic回归模型分析结核患者治疗结局与患者基本特征及治疗情况的相关性。结果3071例涂阳结核患者中男性1683例,女性1388例,2736例(89.1%)治疗成功,335例(10.9%)治疗不成功。多因素分析结果显示涂阳结核患者治疗失败与年龄、治疗分类、痰检复诊次数、实际管理方式相关。结论有关部门应加强对老年患者、复治、未完成痰检复诊、强化期督导患者的监督和管理,提高患者治疗的依从性。Objective To evaluate the treatment outcomes of newly registered smear-positive tuberculosis patients and to determine the factors associated with treatment failure.Methods A retrospective cohort study was conducted in 3071 adult smear-positive tuberculosis patients to register their personal information,follow-up,anti-tb treatment and follow-up.Logisticregression model was established to analyze the correlation between the treatment outcome and the basic characteristics and treatment status of tuberculosis patients.Results Among 3071 smear-positive tuberculosis patients,1683 were male,1388 were female,2736(89.1%)were successfully treated,and 335(10.9%)were unsuccessfully treated.Multivariate analysis showed that the treatment failure of smear-positivetuberculosis patients was related to age,treatment classification,the number of sputum examination,the actual management.Conclusion The relevant departments should strengthen the supervision and management of elderly patients,retreatment,incomplete sputum examination and intensive supervision of patients,so as to improve the treatment compliance of patients.

关 键 词：肺结核 涂阳 治疗结局 成人 

分 类 号：G643[文化科学—高等教育学]