补气养血通络法治疗腰椎管狭窄症的临床研究  

Clinical Study on Treatment of Lumbar Spinal Stenosis with Therapy of Invigorating Qi,Nourishing Blood and Unblocking Collaterals

作　　者：许来峰 李静[2] 李佳 蔡国伟[2] XU Lai-Feng;LI Jing;LI Jia;CAI Guo-Wei(Hubei Provincial Rongjun Hospital,Wuhan 430079 Hubei,China;Dept.of Acupuncture,Union Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022 Hubei,China;College of Acupmoxibustion,Orthopedics and Traumatology,Hubei University of Chinese Medicine/Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion,Wuhan 430065 Hubei,China)

机构地区：[1]湖北省荣军医院,湖北武汉430079 [2]华中科技大学同济医学院附属协和医院针灸科,湖北武汉430022 [3]湖北中医药大学针灸骨伤学院/针灸治未病湖北省协同创新中心,湖北武汉430065

出　　处：《广州中医药大学学报》2020年第12期2319-2325,共7页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(编号:81774410);湖北省卫健委科研项目(编号:ZY2019M041)。

摘　　要：【目的】观察补气养血通络法治疗腰椎管狭窄症的临床疗效。【方法】将108例腰椎管狭窄症患者随机分为治疗组和对照组,每组各54例。治疗组给予服用补气养血通络中药治疗,对照组给予服用腰痹通胶囊治疗,疗程为4周。观察2组患者治疗前和治疗1周、2周、3周、4周后腰部疼痛视觉模拟量表(VAS)评分及腰部疾患日本骨科学会(JOA)评分的变化情况,并评价2组患者的临床疗效及安全性。【结果】(1)疗效方面:治疗4周后,治疗组的优良率为40.7%(22/54),对照组为22.2%(12/54),组间比较,治疗组的优良率明显优于对照组,差异有统计学意义(P<0.05)。(2)VAS评分方面:治疗后各观察时点,2组患者的VAS评分均较治疗前明显降低(P<0.05),且治疗组在治疗1周和2周后对VAS评分的降低作用明显优于对照组,差异均有统计学意义(P<0.05)。(3)JOA评分方面:治疗后各观察时点,2组患者的JOA评分均较治疗前明显改善(P<0.05),且治疗组在治疗2周后对JOA评分的改善作用明显优于对照组,差异均有统计学意义(P<0.05)。(4)安全性方面:治疗过程中,2组患者均无明显的不良事件发生,患者的血、尿常规和肝肾功能也均无明显异常变化。【结论】补气养血通络中药治疗腰椎管狭窄症疗效确切,相比腰痹通胶囊,其疗效更好,起效更快。Objective To observe the therapeutic effect of therapy of invigorating qi,nourishing blood and unblocking collaterals for the treatment of lumbar spinal stenosis.Methods A total of 108 patients with lumbar spinal stenosis were randomly divided into treatment group and control group,with 54 cases in each group.The treatment group was given oral use of Chinese medicine decoction with the actions of invigorating qi,nourishing blood and unblocking collaterals,and the control group was given oral use of Yaobitong Capsules for 4 weeks.Before treatment,one week,2 weeks,3 weeks and 4 weeks after treatment,the scores of visual analogue scale(VAS)for lumbago and the scores of Japanese Orthopaedic Association(JOA)for lumbar diseases were recorded.After treatment,the clinical efficacy and safety of the two groups were evaluated.Results(1)After treatment for4 weeks,the excellent rate of the clinical efficacy in the treatment group was 40.7%(22/54),and that in the control group was 22.2%(12/54).The intergroup comparison showed that the excellent rate of the clinical efficacy in the treatment group was superior to that in the control group,and the difference was statistically significant(P<0.05).(2)At various time points after treatment,VAS pain scores in the two groups were obviously decreased in comparison with those before treatment(P<0.05),and the treatment group had stronger effect on decreasing VAS pain scores one week and 2 weeks after treatment than the control group,the difference being statistically significant(P<0.05).(3)At various time points after treatment,JOA scores in the two groups were obviously improved in comparison with those before treatment(P<0.05),and the treatment group had stronger effect on improving JOA scores 2 weeks after treatment than the control group,the difference being statistically significant(P<0.05).(4)During the trial,no adverse events occurred in the two groups,no abnormal changes were found in the routine test of blood and urine or in the hepatic and renal function either.Conclusion Chi

关 键 词：腰椎管狭窄症 补气养血通络法 腰痹通胶囊 视觉模拟量表评分 日本骨科学会评分 

分 类 号：R274.9[医药卫生—中西医结合] R681.5[医药卫生—中医骨伤科学]