瑞德西韦治疗冠状病毒感染研究的文献计量学分析  

Bibliometrics analysis research on remdesivir for coronavirus

作　　者：彭金林 王磊 席玉梅 李晓晴 吴健林[1] 李国坚[1] 吴继周[1] PENG Jinlin;WANG Lei;XI Yumei;LI Xiaoqing;WU Jianlin;LI Guojian;WU Jizhou(The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China;College of Health and Rehabilitation,Chengdu University of Chinese Medicine,Chengdu 610075,Sichuan Province,China)

机构地区：[1]广西医科大学第一附属医院,南宁市530021 [2]成都中医药大学养生康复学院,四川省成都市610075

出　　处：《内科》2020年第5期513-516,共4页Internal Medicine

基　　金：国家自然科学基金项目(30960170);广西教育厅重点课题基金项目(桂教201202ZD021)。

摘　　要：目的通过文献计量学方法分析瑞德西韦治疗冠状病毒感染的现状。方法检索中国知网、万方数据库、中国生物医学文献服务系统和Pubmed、Web Of Science、Ovid、Embase英文数据库从建库至2020年3月收录的关于瑞德西韦治疗冠状病毒感染的文献,对纳入研究的文献进行文献计量学分析。结果纳入分析的文献共17篇,其中4篇为临床研究(23.53%),13篇为基础研究(76.47%)。发表在美国、英格兰杂志的文献最多,均为不同研究单位合作共同完成相关研究,研究者主要来自美国和加拿大,第一作者单位主要为高校和研究院所,作者多在10人以上,大部分研究(82.35%)获得基金资助。文献中出现频次较高的关键词依次为remdesivir,GS-5734,coronavirus,Ebola virus,SARS-CoV,MERS-CoV,RdRp,RNA polymerases。结论瑞德西韦治疗冠状病毒感染的研究始于5年前,文献数量较少,多数为基础研究,临床研究较少,大部分研究在欧美发达国家完成。Objective To investigate the research status of remdesivir for coronavirus by bibliometrics method.Methods The literature concerning coronavirus treated by remdesivir were searched in the Chinese database of CNKI,Wang Fang Data,CBM,and the English database of Pubmed,Web of Science,Ovid,and Embase from database construction to March 2020.Bibliometrics analysis was performed on the literature enrolled to the research.Results Seventeen literature was enrolled in the research,of which 4 literature belonged to clinical research(23.53%)and 13 to basic research(76.47%).Most of the literature was published in the United States and England,which were related research accomplished together by various research institutes,and their researchers were mainly from the United State and Canada;moreover,the organization in which the first authors affiliated to were mostly colleges and scientific institutes,and with more than 10 participating authors in most of the studies;furthermore,most of the studies(82.35%)received funding.The preferable high-frequency keywords presented as remdesivir,GS-5734,coronavirus,Ebola virus,SARS-CoV,MERS-CoV,RdRp,and RNA polymerases in the enrolled literature.Conclusion The research of remdesivir for coronavirus dates from the past 5 years.The amount of literature is small,most of which are basic research,but with few clinical research.Most of the research is accomplished in developed countries like Europe and America.

关 键 词：冠状病毒 瑞德西韦 文献计量学 

分 类 号：R373.1[医药卫生—病原生物学] R563.1[医药卫生—基础医学]