某院外科系统Ⅰ类切口手术预防用抗菌药物的合理性评价  

Rationality Evaluation of Prophylactic Antibiotics in Patients with TypeⅠIncision Surgical S ystem in a Hospital

作　　者：王萍 张儒军 陈立波 吴雯雯 严江 WANG Ping;ZHANG Ru-jun;CHEN Li-bo;WUWen-wen;YAN Jiang(Jianghan Oilfield General Hospital of Hubei,Qianjiang Hubei 433124,China)

机构地区：[1]湖北江汉油田总医院,湖北潜江433124

出　　处：《抗感染药学》2020年第10期1435-1440,共6页Anti-infection Pharmacy

摘　　要：目的:评价医院外科系统Ⅰ类切口手术患者预防用抗菌药物的合理性。方法:抽取医院2019年间Ⅰ类切口手术患者病历资料874例,统计其Ⅰ类切口手术患者基本信息(姓名、性别、年龄、病历号)、手术名称及手术时间以及预防用抗菌药物名称、使用频次、使用时机、使用时间;分析和评价使用药物的DDDs和DUI值合理性。结果:874例Ⅰ类切口手术患者中预防用药761例(占87.07%),预防用抗菌药物DUI>1的病历为113例(占14.85%),依替米星注射液DUI>1的患者45例(占35.91%);依替米星注射液使用患者232例(占30.49%),头孢替唑227例(占29.83%);预防使用抗菌药物中使用时机在术前30 min^1 h内仅16例(占3.08%),而术后用药和术前>24 h用药分别占37.96%和37.38%。结论:医院外科系统Ⅰ类切口手术患者中预防使用抗菌药物高达87.07%,临床药师与行政部门应积极干预Ⅰ类切口手术抗菌药物的预防使用,加强规范化培训促进临床合理用药。Objective:To evaluate the rationality of prophylactic antibiotics in patients with typeⅠincision surgery in a hospital surgical system.Methods:The medical records of 874 patients with typeⅠincision surgery in 2019 were collected,and the basic information(name,sex,age and medical record number)of the patients with typeⅠincision surgery,the name of the operation and the operation time,the name of the antimicrobial agents for prevention,and the frequency of use,and timing of use,and time of use were counted.The rationality of DDDs and DUI values of drugs used were analyzed and evaluated.Results:Among the 874 patients with typeⅠincision surgery,714 used prophylactic antimicrobials,accouting for 81.69%(714/874),the medical records of preventive antimicrobial agents DUI greater than 1 were 113 cases,accouting for 12.93%(113/874),45 patients with etimicin injection DUI Greater than 1 accounted for5.15%(45/874),232 patients with etimicin injection accounted for 26.54%(232/874),227 patients with ceftezole accounted for 25.97%(227/874);In the prevention of the use of antimicrobial agents,only 16 cases accounted for 1.83%(16/874)between 30 min and 1 hour before surgery,while postoperative medication and medication before 1 to 24 h accounted for 47.14%and 19.22%.respectively.Conclusion:Hospital surgical systemⅠclass incision to prevent the use of antimicrobial drugs in surgical patients is as high as 87.07%;clinical pharmacists and administrative departments should actively intervene in theⅠincision surgery,for preventive usage of antibacterial agents and strengthen standardization training to promote rational clinical drug use.

关 键 词：Ⅰ类切口 预防用药 抗菌药物 DUI 合理用药 

分 类 号：R969.3[医药卫生—药理学]