肝硬化伴肾病患者的肾脏病理类型分析  

Renal pathological characteristics in cirrhotic patients

作　　者：游俊丽 许戎[2] You Junli;Xu Rong(Department of Nephrology,Beijing Huairou Hospital,Beijing 101400,China;Renal Division,Department of Medicine,Peking University First Hospital/Peking University Institute of Nephrology Key Laboratory of Renal Disease,Ministry of Health of China/Key Laboratory of Chronic kidney Disease Prevention and Treatment(Peking University),Ministry of Education,Beijing 100034,China)

机构地区：[1]北京怀柔医院肾内科,101400 [2]北京大学第一医院肾内科,北京大学肾脏疾病研究所,卫生部肾脏疾病重点实验室,慢性肾脏病防治教育部重点实验室(北京大学),100034

出　　处：《中华内科杂志》2020年第11期898-901,共4页Chinese Journal of Internal Medicine

摘　　要：为了解肝硬化伴肾损害患者的肾脏病理类型,本研究回顾性分析2010年1月至2019年9月北京大学第一医院肾内科收治的56例肝硬化伴肾病患者的肾脏病理类型。56例患者的肾脏病理类型具有多样性及复杂性,多种病理类型可在同一患者中存在,其中以IgA肾病最常见(41.1%,23例)。39例患者在肾脏病理结果指导下调整了治疗方案,其中36例患者行糖皮质激素和/或免疫抑制剂治疗,1例患者行利妥昔单抗治疗,1例患者血液透析后肾功能恢复。肾组织活检对肝硬化伴肾病患者临床诊断及治疗有重要指导作用,肝硬化并非肾组织活检的禁忌证。This study is aim to analyze pathological characteristics of kidneys in cirrhotic patients with renal disease.Fifty-six cirrhotic patients with various renal diseases at Peking University First Hospital who underwent percutaneous renal biopsy from January 2010 to September 2019 were evaluated retrospectively.Immunoglobulin A nephropathy(IgAN)was the most common type of kidney biopsy(23 cases,41.1%).Different pathologic types were often overlapping.More than 60% patients were treated with steroids and/or immunosuppressants,and 1 patient with anti-CD20 monoclonal antibody.Percutaneous renal biopsy is important for the diagnosis and treatment in cirrhotic patients with renal disease.

关 键 词：肝硬化 肾病 病理学 肾 活组织检查 肾 

分 类 号：R692[医药卫生—泌尿科学] R575.2[医药卫生—外科学]