腹腔镜前列腺癌根治术患者应用不同麻醉方法的效果及认知功能水平的影响分析  

Analysis of the Effect of Different Anesthesia Methods on Patients Undergoing Laparoscopic Radical Prostatectomy and the Impact of the Cognitive Function

作　　者：马凤亚[1] MA Feng-ya(Department of Anesthesiology,Wujin people's Hospital,Changzhou,Jiangsu Province,213017China)

机构地区：[1]江苏省常州市武进人民医院麻醉科,江苏常州213017

出　　处：《系统医学》2020年第21期19-21,共3页Systems Medicine

摘　　要：目的探究腹腔镜前列腺癌根治术患者应用不同麻醉方法的效果及对认知功能水平的影响。方法选取其中2016年1月—2019年12月就该院接受腹腔镜前列腺癌根治术治疗的80例患者作为研究对象。基于双色球随机抽取,均分成立对照与观察两组,每组40例。两组均实施全麻插管,观察组静脉泵注右美托咪定,对照组则泵注等量生理盐水。统计对比两组麻醉药物使用量、术后情况及认知功能情况。结果观察组麻醉药物使用量(659.3±46.3)mg、(1.6±0.1)mg相较于对照组(786.5±55.2)mg、(2.5±0.3)mg均呈现明显优越性(t=17.353、56.250,P<0.05);两组认知功能水平术前对比差异无统计学意义(P>0.05);术后认知功能水平观察组(26.2±1.2)分相较于对照组(22.8±1.1)分呈现显著优越性(t=17.895,P<0.05);观察组术后躁动及恶心呕吐发生率(2.5%;2.5%)相较于对照组(15.0%;17.5%)呈现明显优越性(χ^2=3.914、5.000,P<0.05);且该组POCD发生率(0.0%)相较于对照组(15.0%)也呈现明显优越性,差异有统计学意义(χ^2=6.486,P<0.05)。结论应用右美托咪定治疗腹腔镜前列腺癌患者效果显著,能降低麻醉药物使用量,进而促进患者术后认知功能的恢复。Objective To investigate the effect of different anesthetic methods on cognitive function in patients undergoing radical resection of laparoscopic prostate cancer. Methods From January 2016 to December 2019 as the time zone, selected among them in the hospital received laparoscopic radical prostatectomy treatment of 80 patients as the study object. Based on the random sampling of two-color ball, the average group was divided into two groups: control and observation,40 cases in each group. General anesthesia intubation was performed in both groups, dexmedetomidine was injected in the observation group and dexmedetomidine was injected in the control group. The dosage, postoperative status and cognitive function of the two groups were compared. Results The amount of narcotic drugs used in the observation group was (659.3±46.3)mg, (1.6±0.1)mg compared Congnitive function level with the control group(786.5±55.2)mg,(2.5±0.3)mg showed significant superiority(t=17.353,56.250,P<0.05);there was no statistically significant difference in between the two groups before operation(P>0.05). Compared with cognitive function level, the control group(22.8±1.1)points, the postoperative observation group (26.2±1.2)points presented significant advantages(t=17.895,P<0.05). The incidence of postoperative restlessness and nausea and vomiting in the observation group (2.5%;2.5%) was significantly superior to that of the control group (15.0%;17.5%)(χ^2=3.914, 5.000, P<0.05);and the occurrence of POCD in this group Compared with the control group (15.0%), the rate (0.0%) is also significantly superior, and the difference was statistically significant(χ^2=6.486,P<0.05). Conclusion The use of dexmedetomidine in the treatment of laparoscopic prostate cancer patients has a remarkable effect, can reduce the use of narcotic drugs, and then promote the recovery of postoperative cognitive function, worthy of further application and promotion.

关 键 词：腹腔镜手术 前列腺癌根治术 麻醉方法 认知功能 

分 类 号：R614[医药卫生—麻醉学]