不同微波烘烤程度的山绿茶炮制品降血压作用比较研究  

Comparative Study on the Antihypertensive Effects of Processed Products of Different Ilex Hainanensis Merr.Processed by Microwave Baking

作　　者：魏江存 谢臻[2] 陈勇[2] 郑锡任[2,3] 李耀华 马家宝[3] 韩倩[2] WEI Jiangcun;XIE Zhen;CHEN Yong;ZHENG Xiren;LI Yaohua;MA Jiabao;HAN Qian(Guangxi International Zhuang Medical Hospital,Nanning 530201,China;Guangxi University of Chinese Traditional Medicine,Nanning 530200,China;The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,China)

机构地区：[1]广西国际壮医医院,南宁530201 [2]广西中医药大学,南宁530200 [3]广西中医药大学第一附属医院,南宁530023

出　　处：《中国现代应用药学》2020年第20期2465-2468,共4页Chinese Journal of Modern Applied Pharmacy

基　　金：国家自然科学基金项目(81060344,81660701);广西自然科学基金项目(2016GXNSFAA380148);广西中药药效研究重点实验室(17-259-20);广西中医药大学2018年广西一流学科建设项目重点课题(2018XK060);广西壮族自治区食品药品监督管理局课题(YTT17003,YJJ16003);国家中医药管理局科研三级实验室中(壮)药化学与质量分析实验室(国中医药发2009[21]号)。

摘　　要：目的对广西特产药材山绿茶进行中药炮制实验研究,并考察其降血压作用。方法使用不同炮制方法对山绿茶进行炮制;采用尾动脉法测定山绿茶不同炮制品对原发性高血压大鼠(spontaneously hypertensive rats,SHR)血压的影响。结果共得到5种山绿茶炮制品;与模型组比较,不同山绿茶炮制品均有明显的降血压效果。不同微波炮制品中,以60 g药材微波11 min组降压作用最佳。结论山绿茶最佳微波炮制工艺为60 g药材微波11 min,此方法炮制出的山绿茶药材对SHR的降压效果最好。OBJECTIVE To study the processing of Chinese herbal medicine Ilex hainanensis Merr.produced in Guangxi,and to carry out an experimental study on its antihypertensive effect.METHODS Ilex hainanensis Merr.was processed by different processing.The effects of different processed products of Ilex hainanensis Merr.on the blood pressure of spontaneously hypertensive rats(SHR)were measured by tail artery method.RESULTS Five types of Ilex hainanensis Merr.processed products were obtained.Compared with the model group,the different processing Ilex hainanensis Merr.had obvious effect of lowering blood pressure.For different microwave processed varieties,the antihypertensive effect of 60 g microwave 11 min group was the best.CONCLUSION The best microwave processing technology of Ilex hainanensis Merr.is microwave of 60 g of medicinal materials for 11 min.The Ilex hainanensis Merr.prepared by this method has the best antihypertensive effect on SHR.

关 键 词：山绿茶 中药炮制 原发性高血压大鼠 药效 微波 

分 类 号：R285.5[医药卫生—中药学]