遗传性大肠癌患者一级亲属的大肠癌认知、态度及筛查行为研究  

Status quo and influencing factors about colorectal cancer screening among first degree relatives of hereditary colorectal cancer patients

作　　者：吴晓丹[1] 郭志东 丘雪 潘志忠[1] 张美芬[3] WU Xiaodan;GUO Zhidong;QIU Xue;PAN Zhizhong;ZHANG Meifen(Department of Colorectal Surgery,State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Sun Yat-sen University Cancer Center,Guangzhou,510060,China)

机构地区：[1]中山大学肿瘤防治中心,华南肿瘤学国家重点实验室,肿瘤医学协同创新中心,广州市510060 [2]中山大学附属第一医院产房 [3]中山大学护理学院

出　　处：《中国护理管理》2020年第11期1627-1632,共6页Chinese Nursing Management

基　　金：国家重点研发计划资助-NCRCC(2017YFC0908202);广东省医学科研基金(A2019004)。

摘　　要：目的:分析遗传性大肠癌患者一级亲属的大肠癌相关知识、态度及筛查行为特征。方法:应用修订的香港中文大学“结直肠癌认知调查问卷”和一般资料调查表,对274例遗传性大肠癌患者的一级亲属进行调查,分析该人群的大肠癌相关知识、对大肠癌的态度及结肠镜筛查情况,探讨大肠镜筛查的影响因素。结果:遗传性大肠癌患者一级亲属对大肠癌具有较高认知者为165例(60.2%),部分认知者为65例(23.7%),低认知者为44例(16.0%);144例(52.6%)研究对象对大肠癌筛查态度较积极;63例(23.0%)研究对象接受过结肠镜筛查,个体的大肠癌认知水平、先证者诊断、年龄、性别、婚姻状况、居住地、医疗保险状况、是否患有慢性病是其大肠癌筛查行为的影响因素。结论:遗传性大肠癌患者一级亲属的大肠癌认知水平整体较高,态度较积极,但结肠镜筛查率较低,应采取措施提高部分遗传性大肠癌患者一级亲属的大肠癌认知水平及大肠癌筛查率,以更好地防治大肠癌。Objective:To investigate the cog nition,attitude and behavior about colorectal cancer and the screening of colorectal cancer and its relevant factors among first degree relatives of hereditary colorectal cancer patients in Guangzhou.Methods:Totally 274 subjects were investigated by a self-designed demographic questionnaire and the Chinese version of Cognitive Questionnaire for Colorectal Cancer and were analyzed by chisquare test and logistic regressive.Results:There were 165 cases(60.2%)had a high level of cognition about colorectal cancer,65 cases(23.7%)had middle level of cognition about colorectal cancer and 44 cases(16.0%)had a low level of cognition about colorectal cancer.144 cases(52.6%)had positive attitude about colorectal cancer screening.63 cases(23.0%)had accept colorectal screening.Multivariate logistic regression analysis showed that colorectal cancer cognition,index patiemt's diagnosis,age,sex,marital status,medical insurance and suffering from chronic diseases were related to the factors of behavior about colorectal screening(P<0.05).Conclusion:The level of cognition about colorectal cancer among first degree relatives of hereditary colorectal cancer patients was a little high.However their screening rate of colorectal cancer was low.Medical staff should pay attention to relevant factors and develop targeted intervention to improve the level of cognition among first degree relatives of hereditary colorectal cancer patients and to promote their screening behavior.

关 键 词：遗传性大肠癌 一级亲属 认知 态度 行为 筛查 

分 类 号：R47[医药卫生—护理学]