电子支气管镜下高频电切配合冷冻及局部给药对肉芽增殖型支气管结核的临床疗效  

Clinical effect of high-frequency electric resection under electronic bronchoscope combined with freezing and local administration on granulation bronchial tuberculosis

作　　者：张学钰[1] 万力 钟诚[1] 肖小灏[1] 刘兰贞[1] ZHANG Xue-yu;WAN Li;ZHONG Cheng;XIAO Xiao-hao;LIU Lan-zhen(The Second Department of Internal Medicine Jiangxi Chest Hospital,Jiangxi Province,Nanchang330006,China)

机构地区：[1]江西省胸科医院内二科,江西南昌330006

出　　处：《中国当代医药》2020年第32期31-34,共4页China Modern Medicine

基　　金：江西省卫健委科技计划项目(20204742)。

摘　　要：目的探讨电子支气管镜下高频电切配合冷冻及局部给药对肉芽增殖型支气管结核的临床疗效。方法选取江西省胸科医院2018年1月~2019年11月收治的40例肉芽增殖型支气管结核患者作为研究对象,按照抽签法分为对照组(20例)与观察组(20例)。对照组采用冷冻及局部给药治疗,观察组予以电子支气管镜下高频电切配合冷冻治疗及局部给药治疗,比较两组的治疗总有效率、结核病灶吸收率、治疗次数及并发症发生情况。结果观察组的总有效率高于对照组,差异有统计学意义(P<0.05);观察组结核病灶总吸收率高于对照组,差异有统计学意义(P<0.05);观察组的平均治疗次数少于对照组,差异有统计学意义(P<0.05);两组的并发症发生率比较,差异无统计学意义(P>0.05)。结论电子支气管镜下高频电切配合冷冻治疗及局部给药治疗肉芽增殖型支气管结核的临床效果显著,且安全性高,建议在临床上进一步推广。Objective To analyze the clinical effect of high-frequency electrocision combined with cryotherapy and local administration in the treatment of granuloproliferative bronchial tuberculosis under electronic bronchoscopy.Methods A total of 40 patients with granulomatous bronchial tuberculosis admitted to Jiangxi Chest Hospital from January 2018 to December 2019 were selected as the research objects,they were divided into the control group(20 cases)and the observation group(20 cases)according to the lottery method.The patients in the control group were treated with cryotherapy and local administration,and the patients in the observation group were treated with electronic bronchoscopy under high frequency electrocision combined with cryotherapy and local administration.The total treatment efficiency,tuberculosis lesion absorption rate,number of treatments and complications were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05);the absorption rate of tuberculosis lesions in the observation group was higher than that of the control group,the difference was statistically significant(P<0.05);the average number of treatment of the observation group was less than that of the control group,and the difference was statistically significant(P<0.05);the incidence of complications between the two groups was not statistically significant(P>0.05).Conclusion Electronic bronchoscopy combined with high-frequency electroresection combined with cryotherapy and local administration in the treatment of granulomatous proliferative bronchial tuberculosis has a significant clinical effect and high safety.It is recommended to be further promoted clinically.

关 键 词：电子支气管镜 高频电切 冷冻 局部给药 肉芽增殖型支气管结核 

分 类 号：R655.3[医药卫生—外科学]