膀胱内肾源性腺瘤合并双肾重度积水1例报告并文献复习  

Nephrogenic adenoma in the bladder with severe hydronephrosis of both kidneys:a case report and literature review

作　　者：张文圣[1] 陶韬 ZHANG Wen-sheng;TAO Tao(Department of Urology,Jiujiang No.1 People′s Hospital,Jiangxi Province,Jiujiang332000,China)

机构地区：[1]江西省九江市第一人民医院泌尿外科,江西九江332000

出　　处：《中国当代医药》2020年第32期197-199,共3页China Modern Medicine

摘　　要：回顾性分析1例膀胱内肾源性腺瘤,复习相关文献,并总结其临床与病理学特征。患者,女,17岁,既往有泌尿道手术史。膀胱镜下见膀胱黏膜局部隆起,呈乳头状。病理组织:膀胱黏膜呈乳头增生,部分钉突状,少量腺管形成。免疫组化结果:PAX-2、PAX-8、CK7、34βE12均阳性,而GATA-3、P63均阴性。膀胱内肾源性腺瘤是泌尿系统一种罕见的良性增生性病变,患者常伴有泌尿道手术病史,诊断主要依靠临床病理学和免疫组化特征,治疗主要为经尿道膀胱病损切除,术后需密切复查。A case of nephrogenic adenoma in the bladder was retrospectively analyzed,the relevant literature was reviewed,and its clinical and pathological characteristics were summarized.The patient was a 17-year-old female with a history of urinary tract surgery.Under the cystoscope,the bladder mucosa was partially uplifted in papillary.Pathological tissue indicated the bladder mucosa presented with hyperplasia of papillae,part of spike-like,and a small number of glands formed.Immunohistochemical results displayed PAX-2,PAX-8,CK7,and 34βE12 were all positive,while GATA-3 and P63 were all negative.Nephrogenic adenoma in the bladder is a rare benign proliferative disease of the urinary system.Patients are often accompanied by a history of urinary tract surgery.The diagnosis mainly depends on clinical pathological and immunohistochemical characteristics.The treatment to remove the affected bladder lesion via urethra and close re-examination is necessary after surgery.

关 键 词：膀胱内肾源性腺瘤 肾小管种植理论 肾小管特异性上皮标志物 肾积水 

分 类 号：R694[医药卫生—泌尿科学]