2008-2018年浙江省戒毒药物维持治疗情况分析  

Performance of methadone maintenance treatment in Zhejiang, 2008–2018

作　　者：陈卫永[1] 马瞧勤[1] 周欣[1] 姜婷婷[1] 陈婉君 陈琳[1] 王憓[1] 郑锦雷[1] Chen Weiyong;Ma Qiaoqin;Zhou Xin;Jiang Tingting;Chen Wanjun;Chen Lin;Wang Hui;Zheng Jinlei(AIDS and HIV Prevention and Control Institute,Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou 310051,Zhejiang,China)

机构地区：[1]浙江省疾病预防控制中心艾滋病与性病预防控制所,浙江杭州310051

出　　处：《疾病监测》2020年第10期899-903,共5页Disease Surveillance

基　　金：浙江省卫生健康科技计划(No.2021KY617);浙江省医药卫生科技项目(No.2020RC051)。

摘　　要：目的描述2008—2018年浙江省戒毒药物维持治疗工作情况,分析存在的问题,提出科学建议,为促进全省戒毒药物维持治疗工作、发挥禁毒与预防艾滋病作用提供科学依据。方法从"中国疾病预防控制中心美沙酮维持治疗(MMT)管理信息系统"和各戒毒药物维持治疗门诊数据报表中,采集2008—2018年全省戒毒药物维持治疗工作数据,采用SPSS 21.0软件进行描述性分析。结果 2008—2018年全省已建成MMT机构105家,累计治疗人数超过1.8万;年度治疗人数最高为2010年8 060人,最低为2018年3 635人;MMT剂量为39.91~43.83 mg/d,HIV阳转率为0.07%~0.08%;年保持率为60.17%~84.37%,呈缓慢上升趋势,治疗退出人员自2011年起超过新入组人员。人类免疫缺陷病毒(HIV)、丙型肝炎病毒(HCV)、梅毒检测率逐年增长,HIV、HCV和梅毒阳性率分别为0.19%~0.98%、38.36%~62.24%和4.36%~6.96%。结论浙江省MMT存在治疗人数下滑明显、服药剂量偏低等问题,需加大MMT服务可及性,提高工作人员服务能力和服务质量,降低治疗脱失,更好地发挥MMT在禁毒与预防艾滋病中的作用。Objective To analyze the performance of methadone maintenance treatment(MMT) in Zhejiang province from2008 to 2018, found existing problems and provide evidence for the improvement of MMT in drug use control and HIV infection prevention. Methods MMT data in Zhejiang from 2008 to 2018 were collected from national MMT information management system and MMT clinic reports for a descriptive analysis with SPSS 21.0. Results A total of 105 MMT clinics were built from 2008 to 2018 which have provided treatment services for over 18 000 persons. The highest number of treatment was 8 060 in 2010. The lowest number of treatment was 3 635 in 2018. The treatment dosage of MMT was between 39.91 mg/d and 43.83 mg/d. The positive conversion rate was between 0.07% and 0.08%. The annual treatment retention rate was between60.17% and 84.37%, showing a gradual increasing trend. The number of persons who quitted the treatment began to exceed the number of new participants in 2011. The testing rates of HIV, HCV and syphilis were 0.19%–0.98%, 38.36%–62.24% and4.36%–6.96% respectively, showing an increase trend with year. Conclusion MMT in Zhejiang had an obvious decrease in number of treatments, and the treatment dosage was low. It is necessary to improve the accessibility, quality of MMT service and clinic staff capability and reduce treatment dropping out for the better drug use control and HIV infection prevention.

关 键 词：阿片类成瘾者 美沙酮维持治疗 治疗情况 

分 类 号：R211[医药卫生—中医学] R749.64