冠状病毒与输血传播性疾病的相关性探讨  

Relationship between coronavirus and transfusion transmitted diseases

作　　者：武文 郭兴莹 马红霞 黄象艳 Wu Wen;Guo Xingying;Ma Hongxia;Huang Xiangyan(Department of Blood Transfusion,The 960th Hospital of the People’s Liberation Army(PLA)Joint Logistics Support Force,Jinan 250031,China)

机构地区：[1]解放军联勤保障部队第九六○医院输血医学科,济南250031

出　　处：《中华实验和临床病毒学杂志》2020年第4期378-381,共4页Chinese Journal of Experimental and Clinical Virology

摘　　要：新型冠状病毒(2019-nCoV)、严重急性呼吸综合征(severe acute respiratory syndrome coronavirus,SARS-CoV)及中东呼吸综合征(Middle East respiratory syndrome coronavirus,MERS-CoV)对全球公共卫生安全造成严重威胁。虽然冠状病毒(Coronavirus,CoV)的主要感染途径为呼吸道感染,既往呼吸道病毒的研究和目前2019-nCoV相关报道表明该类病毒导致输血传播性疾病(transfusion transmitted disease,TTD)的可能性较小,但可在患者血浆中检测到病毒RNA,因此,尚无证据完全排除其通过输血传播的可能性。本文结合CoV特征、经血液传播途径的理论研究及数据分析,对CoV与TTD的相关性进行探讨,总结了采供血机构针对新冠肺炎(COVID-19)疫情发展现状应采取的防控措施,为保障COVID-19疫情防控期间临床用血安全提供了2019-nCoV的输血传播风险分析和应对策略。Novel coronavirus(2019-nCoV),severe acute respiratory syndrome coronavirus(SARS-CoV),and Middle East respiratory syndrome coronavirus(MERS-CoV)had posed a serious threat to global public health security.Although the main route of infection of the coronavirus is respiratory infection and it is less likely to cause transfusion transmitted disease(TTD),there was no evidence to completely rule out the possibility of transmission through blood transfusion because of the presence of the virus RNA in the plasma of patients.Based on the characteristics of the coronavirus and theoretical research and data analysis of the route of blood transmission,this paper discusses the relationship between coronavirus and TTD,summarizes the prevention and control measures that should be taken by blood collection and supply institutions,and provides the risk analysis and coping strategies of blood transfusion transmission of 2019-nCoV to ensure the blood safety during the COVID-19 epidemic situation.

关 键 词：新型冠状病毒 输血传播性疾病 传播途径 血液安全 

分 类 号：R563.1[医药卫生—呼吸系统] R457.1[医药卫生—内科学]