同型半胱氨酸水平对冠心病患者PCI术后预后的影响  

Impact of Homocysteine Level on Prognosis of Patients with Coronary Artery Disease After Percutaneous Coronary Intervention

作　　者：陈琳[1] 叶加宝[1] CHEN Lin;YEJia-bao(Department of Cardiology,Suzhou Hospital Affiliated to Nanjing Medical University,Suzhou,Jiangsu,215001,China)

机构地区：[1]南京医科大学附属苏州医院心内科,江苏苏州215001

出　　处：《中国血液流变学杂志》2020年第2期170-172,共3页Chinese Journal of Hemorheology

摘　　要：目的 探讨不同水平血同型半胱氨酸(Hcy)对冠心病患者行经皮冠状动脉介入治疗(PCI)术后预后的影响.方法 将接受PCI治疗的104例冠心病患者根据其血Hcy水平分为2组,记录住院期间及出院后12个月主要心血管事件(MACE)发生率.结果 Hcy升高组在住院期间MACE发生率与Hcy正常组相比差异无统计学意义(P>0.05),但随访12个月期间靶血管血运重建率及MACE的发生率显著高于Hcy正常组(P<0.05).结论 Hcy水平升高影响冠心病患者PCI术后的预后,对于Hcy水平升高的冠心病患者,应积极进行干预,以减少PCI术后心血管事件的发生.Objective To investigate the effect of different levels of homocysteine(Hey)on prognosis of patients with coronary artery disease after percutaneous coronary intervention(PCI).Methods 104 patients with coronary heart disease after PCI were divided into two groups according to their blood Hey levels.The incidence of major cardiovascular events(MACE)was recorded during hospitalization and 12 months after discharge.Results There was no statistically significant difference in the incidence of MACE between the two groups during hospitalization(P>0.05).However,during the follow-up period of 12 months,the target vessel revascularization rate and the incidence of MACE in the elevated Hey group were significantly higher than those in the normal Hey group(P<0.05).Conclusion The increase of Hey level may affect the prognosis of patients with coronary heart disease after PCI.We should intervene to the patients with coronary artery disease with elevated Hey level to reduce the incidence of cardiovascular events after PCI.

关 键 词：同型半胱氨酸 冠心病 冠状动脉支架治疗 预后 

分 类 号：R541.4[医药卫生—心血管疾病]