血管内介入栓塞术和开颅夹闭术治疗颅内动脉瘤疗效比较  

Comparison of the Effect of Endovascular Embolization and Transcranial Clipping in the Treatment of Intracranial Aneurysm

作　　者：张峰[1] 高飞 于剑[1] 王位坐 张黎明[1] 王亮[1] ZHANG Feng;GAO Fei;YU Jian;WANG Wei-zuo;ZHANG Li-ming;WANG Liang(Department of Neurosurgery,the Fourth Affiliated Hospital of China Medical University,Shenyang,Liaoning,110032,China;Department of Neurosurgery,Affiliated Central Hospital of Shenyang Medical College,Shenyang,Liaoning,110024,China)

机构地区：[1]中国医科大学附属第四医院神经外科,辽宁沈阳110032 [2]沈阳医学院附属中心医院神经外科,辽宁沈阳110024

出　　处：《中国血液流变学杂志》2020年第2期204-206,227,共4页Chinese Journal of Hemorheology

摘　　要：目的 探讨血管内介入栓塞术和开颅夹闭术治疗颅内动脉瘤临床疗效比较.方法 对2014年1月—2019年1月收治的66例颅内动脉瘤患者的临床资料进行回顾性抽取分析,按照治疗方案的不同分为开颅治疗组和介入治疗组.其中,开颅治疗组32例,行开颅夹闭手术治疗,介入治疗组34例,实施血管内介入栓塞术治疗.对两组患者进行手术时间、手术费用及住院时间的比较,并进行术中及术后主要并发症发生率以及短期预后等情况的比较.结果 介入治疗组手术时间及住院天数均显著优于开颅治疗组,两者比较差异具有统计学意义(P<0.05);介入治疗组手术费用显著高于开颅治疗组,差异具有统计学意义(P<0.05);两组患者术中及术后并发症发生率情况对比差异无统计学意义(P>0.05);短期预后情况对比差异无统计学意义(P>0.05).结论 血管内介入栓塞术及开颅夹闭手术治疗颅内动脉瘤均可取得较好的疗效,血管介入栓塞术用时少,费用高;开颅夹闭手术用时长,费用相对较低,临床可依据患者具体情况进行治疗方法的选择.Objective To compare the clinical effect of interventional embolization and transcranial clipping in the treatment of intracranial aneurysm.Methods The clinical data of 66 patients with intracranial aneurysm admitted in the Fourth Affiliated Hospital of China Medical University from January 2014 to January 2019 were analyzed retrospectively.According to the different treatment schemes,they were divided into two groups:craniotomy group and interventional treatment group.Among them,32 cases in the craniotomy group were treated by open clamping operation,34 cases in the interventional treatment group were treated by intravascular interventional embolization.The operation time,operation cost and hospitalization time of the two groups were compared,and the incidence of major complications and short-term prognosis were compared.Results The operation time and hospitalization days of the interventional treatment group were significantly better than those of the craniotomy group,the difference was statistically significant(P<0.05);the operation cost of the interventional treatment group was significantly higher than that of the craniotomy group,the difference was statistically significant(P<0.05);there was no significant difference between the two groups in the incidence of intraoperative and postoperative complications(P>0.05);there was no significant difference in the short-term prognosis(P>0.05).Conclusion Both endovascular embolization and transcranial clipping can achieve better results in the treatment of intracranial aneurysms.The time of endovascular embolization is less and the cost is higher;the time of transcranial clipping is longer and the cost is relatively lower.The clinical treatment can be selected according to the specific situation of patients.

关 键 词：血管内介入栓塞术 开颅夹闭术 颅内动脉瘤 疗效 

分 类 号：R651.12[医药卫生—外科学]