病毒性角膜内皮炎的研究现状  

Research status of virus-related corneal endotheliitis

作　　者：李燕玲 苏旺铭 何小辉[1] Yan-Ling Li;Wang-Ming Su;Xiao-Hui He(Department of Ophthalmology, the Second Hospital of Longyan City, Longyan 364000, Fujian Province, China)

机构地区：[1]中国福建省龙岩市第二医院眼科中心,364000

出　　处：《国际眼科杂志》2020年第12期2074-2078,共5页International Eye Science

摘　　要：病毒性角膜内皮炎诱因多样,病因复杂,发病机制尚不完全明确,临床表现多样,目前无统一分类,辅助诊断技术不断提高,环媒恒温扩增法、各种PCR对疾病的诊断有一定的辅助作用。但在临床上还主要依靠临床表现、病史来诊断,其治疗临床上主要以抗病毒联合糖皮质激素为主,耐药病毒株越来越多,复发率高,迫切需要研究新药及新的治疗方法,基因工程药物比如疫苗、解旋-引物酶抑制剂、趋化因子受体等实验研究为病毒性角膜内皮炎的治疗带来希望。本文旨在对目前病毒性角膜内皮炎的相关研究作一综述。The virus-related corneal endotheliitis has diverse inducement,complex etiology,unclear pathogenesis,diverse clinical manifestations.There is no unified classification at present.Auxiliary diagnosis technology is improving constantly,loop-mediated isothermal amplification and all kinds of PCR have a certain auxiliary role in the diagnosis of this disease.But the diagnosis also mainly relys on history and clinical manifestation in clinic.Anti-viral drug and glucocorticoid are the main treatment.Virus-related corneal endotheliitis has high recurrence rate,so there is an urgent need to research new drugs and new treatment.Experiment researches of genetic engineering drugs,such as vaccines,unwinding-primers enzyme inhibitors,and chemokine receptors,bring hope to the treatment of virus-related corneal endotheliitis.The purpose of this article is to review the related research of virus-related corneal endotheliitis.

关 键 词：病毒 角膜内皮炎 辅助诊断技术 治疗 

分 类 号：S85[农业科学—兽医学]