中药调控能量代谢治疗神经退行性疾病的研究进展  

Research Progress of Traditional Chinese Medicine Regulating Energy Metabolism in the Treatment of Neurodegenerative Diseases

作　　者：郭园园[1,2] 郑琴[1,2] 胡鹏翼[1,2] 杨明[1,2] 章德林 唐宇[1,2] 罗俊[1,2] 朱梅芳[1,2] 吴海霞 吴玲[1,2] 张科楠[1,2] GUO Yuanyuan;ZHENG Qin;HU Pengyi;YANG Ming;ZHANG Delin;TANG Yu;LUO Jun;ZHU Meifang;WU Haixia;WU Ling;ZHANG Kenan(Jiangxi University of Chinese Medicine,Nanchang 330004 Jiangxi,China;Key Laboratory of Modern Preparation of Chinese Medicine,Ministry of Education,Nanchang 330004 Jianxi,China)

机构地区：[1]江西中医药大学,江西南昌330004 [2]现代中药制剂教育部重点实验室,江西南昌330004

出　　处：《中药新药与临床药理》2020年第11期1384-1388,共5页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国家自然科学基金项目(81860874);江西省科技创新人才重点项目(20171BCB18001);江西省教育厅科学技术研究重点项目(GJJ170699)。

摘　　要：神经退行性疾病是一类发病机制复杂的疾病。近年来,大量研究表明中药对神经退行性疾病有治疗作用。该文综述了中药通过线粒体能量代谢、葡萄糖和胰岛素信号等能量代谢通路治疗多种神经退行性疾病的研究进展,以期为神经退行性疾病的治疗提供新思路。Neurodegenerative disease is a kind of disease with complex pathogenesis.In recent years,a large number of studies have shown that traditional medicine has a therapeutic effect on neurodegenerative diseases.This paper reviews the research progress of traditional medicine in the treatment of various neurodegenerative diseases through energy metabolism pathways such as mitochondrial energy metabolism,glucose and insulin signaling,in order to provide new ideas for the treatment of neurodegenerative diseases.

关 键 词：中药 能量代谢 葡萄糖代谢 胰岛素 线粒体 神经退行性疾病 

分 类 号：R285.5[医药卫生—中药学]