PtfV1与老年高血压患者EAT厚度的相关性研究  

Correlation between PtfV1 and thickness of EAT in elderly patients with hypertension

作　　者：赵枫萍[1] 沈军辉[1] 韩晓娟 张小琴[1] Zhao Fengping;Shen Junhui;Han Xiaojuan;Zhang Xiaoqin(ECG Room,Shanghai Fengxian Central Hospital(South Branch),Shanghai Sixth People's Affiliated to Hospital Shanghai Jiaotong University,Shanghai,201499,China)

机构地区：[1]上海交通大学附属第六人民医院南院奉贤区中心医院心电图室,上海201499

出　　处：《西南国防医药》2020年第11期981-984,共4页Medical Journal of National Defending Forces in Southwest China

基　　金：上海市奉贤区科技发展基金项目计划(20181704)。

摘　　要：目的探讨心电图V1导联P波终末电势(Ptf V1)与老年高血压患者心外膜脂肪组织(EAT)厚度的相关性。方法选取2017年9月~2019年9月住院患者100例,根据Ptf V1是否>40 mm/s分为高Ptf V1组35例及低Ptf V1组65例,比较两组患者EAT厚度并分析Ptf V1与EAT厚度的相关性。结果高Ptf V1组患者高血压危险分层、BMI、合并高脂血症的比例、LVD、LVDD、LVRT高于低Ptf V1组,E/A高Ptf V1组低于低Ptf V1组(P <0.05);高Ptf V1组患者舒张末期及收缩末期EAT厚度均高于低Ptf V1组(P <0.01);Ptf V1与舒张末期EAT厚度的相关系数为0.525,与收缩末期EAT厚度的相关系数为0.711(P <0.01);单因素及多因素Logistic回归显示高血压危险分层、BMI、高脂血症、E/A和EAT厚度与高Ptf V1相关,多因素回归模型显示各因素均与高Ptf V1的发生相关,且关联程度由高至低依次为收缩末期EAT厚度、舒张末期EAT厚度、高血压危险分层、高脂血症、BMI(OR分别为1.64、1.55、1.50、143、1.27,P <0.01)。结论 Ptf V1与老年高血压患者EAT厚度呈正相关,高Ptf V1对于高血压患者合并代谢综合征的风险有一定提示作用。Objective To explore the correlation between the P-wave terminal force in lead V1(PtfV1) and the thickness of epicardial fat tissue(EAT) in elderly patients with hypertension. Methods A total of 100 patients admitted to our hospital from September 2017 to September 2019 were selected and divided into a high-Ptf V1 group(n=35) and a low-Ptf V1 group(n=65) according to whether the Ptf V1 was greater than 40 mm/s. The thickness of EAT was compared between the two groups and the correlation between Ptf V1 and thickness of EAT was analyzed. Results The risk stratification of hypertension, BMI, the proportion of hypertensive patients accompanied by hyperlipidemia, left ventricular internal diameter(LVD), left ventricular diastolic diameter(LVDD), and left ventricular isovolumic relaxation time(LVRT) in the high-Ptf V1 group were higher than those in the low-Ptf V1 group, and E/A was lower than that in the low-Ptf V1 group(P < 0.05). Both the end-diastolic thickness of EAT and end-systolic thickness of EAT in the high-Ptf V1 group were higher than those in the low-Ptf V1 group(P < 0.01). The correlation coefficient between Ptf V1 and end-diastolic thickness of EAT was 0.525, and that between Ptf V1 and end-systolic thickness of EAT was 0.711(P <0.01). The univariate and multivariate logistic regression model showed that the risk stratification of hypertension, BMI,hyperlipidemia, E/A, and thickness of EAT were correlated with high Ptf V1. The multivariate regression model showed that all the factors above were correlated with the occurrence of high Ptf V1, and the end-systolic thickness of EAT was the most correlated with high Ptf V1(OR =1.64), followed by end-diastolic thickness of EAT(OR =1.55), risk stratification of hypertension(OR =1.50),hyperlipidemia(OR=1.43), and BMI(OR=1.27)(P < 0.01). Conclusion Ptf V1 is correlated with the thickness of EAT in elderly patients with hypertension and high Ptf V1 may suggest that hypertensive patients are at risk of accompanied metabolic syndromes.

关 键 词：P波终末电势 高血压 老年 心外膜脂肪组织 相关性分析 

分 类 号：R544.1[医药卫生—心血管疾病]