早期内镜治疗老年重症急性胆源性胰腺炎的临床效果  

Clinical Effect of Early Endoscopic Treatment for Severe Acute Biliary Pancreatitis in the Elderly

作　　者：吴舟[1] WU Zhou(Fuzhou First Hospital,Fuzhou 350009,China)

机构地区：[1]福州市第一医院,福建福州350009

出　　处：《中外医学研究》2020年第32期17-19,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨早期内镜治疗老年重症急性胆源性胰腺炎的临床效果。方法:选择122例老年重症急性胆源性胰腺炎患者为研究对象,将其随机分为对照组(62例)和观察组(60例)。对照组采用传统手术治疗,观察组采用早期内镜治疗。比较两组治疗效果。结果:观察组腹痛缓解时间(5.64±1.27)d,血淀粉酶恢复时间(6.59±1.44)d,胰周积液好转时间(5.89±1.32)d,均早于对照组,差异有统计学意义(P<0.05)。观察组总有效率96.67%,高于对照组的74.19%,差异有统计学意义(P<0.05)。观察组Ranson评分(1.15±0.19)分,APACHE-Ⅱ评分(5.01±0.23)分,VAS评分(1.12±0.15)分,均低于对照组,差异有统计学意义(P<0.05)。观察组TNF-α(1.02±0.07)μg/ml,ET-1(3.10±0.15)ng/L,CRP(71.56±6.38)mg/L,均低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为1.67%,低于对照组的20.97%,差异有统计学意义(P<0.05)。结论:对老年重症急性胆源性胰腺炎患者实施早期内镜治疗的效果显著。Objective:To explore the clinical effect of early endoscopic treatment for severe acute biliary pancreatitis in the elderly.Method:A total of 122 elderly patients with severe acute biliary pancreatitis were selected as the study subjects and randomly divided into the control group(62 cases)and the observation group(60 cases).The control group was treated with traditional surgery,the observation group was treated with early endoscopic treatment.The therapeutic effects of the two groups were compared.Result:The remission time of abdominal pain was(5.64±1.27)d,the recovery time of serum amylase was(6.59±1.44)d,and the improvement time of peripancreatic effusion was(5.89±1.32)d in the observation group,which were all earlier than those in the control group,the differences were statistically significant(P<0.05).The total effective rate of the observation group was 96.67%,which was higher than 74.19%of the control group,and the difference was statistically significant(P<0.05).The Ranson score was(1.15±0.19)points,APACHE-Ⅱscore was(5.01±0.23)points and VAS score was(1.12±0.15)points in the observation group,which were lower than those in the control group,and the differences were statistically significant(P<0.05).The TNF-αwas(1.02±0.07)μg/ml,ET-1 was(3.10±0.15)ng/L,and CRP was(71.56±6.38)mg/L in the observation group,which were all lower than those in the control group,and the differences were statistically significant(P<0.05).The complication rate in the observation group was 1.67%,which was lower than 20.97%in the control group,and the difference was statistically significant(P<0.05).Conclusion:The effect of early endoscopic treatment on elderly patients with severe acute biliary pancreatitis is significant.

关 键 词：内镜 重症急性胆源性胰腺炎 老年 并发症 

分 类 号：R657.51[医药卫生—外科学]