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作 者:郭琪[1] 臧希卉[1] 孙柳燕[1] 吴东林[1] 李静[1] 杨显达[1] GUO Qi;ZANG Xi-hui;SUN Liu-yan;WU Dong-lin;LI Jing;YANG Xian-da(Virus Laboratory,Jilin Provincial Center for Disease Control and Prevention,Changchun,Jilin 130062,China)
机构地区:[1]吉林省疾病预防控制中心病毒检验所,吉林长春130062
出 处:《中国卫生检验杂志》2020年第21期2617-2621,共5页Chinese Journal of Health Laboratory Technology
基 金:吉林省卫生计生自筹经费课题(2015ZC033)。
摘 要:目的通过分析2014年-2018年吉林省新报告HIV/AIDS病例首次CD4^+T淋巴细胞(简称CD4细胞)检测情况,为艾滋病防治工作提供可靠的科学依据。方法每年1月下载艾滋病网络直报病例报告卡和7月下载随访管理数据库,采用SPSS 25.0软件进行数据分析。结果2014年-2018年新发现HIV/AIDS患者首次CD4细胞检测比例呈上升趋势(P<0.05);5年中AIDS病例首次CD4计数的中位数分别为128.5个/μl、80.0个/μl、83.0个/μl、71.0个/μl和63.0个/μl;不同年龄、文化程度、职业、婚姻状况和传播途径首次CD4检测结果组间差异有统计学意义(P<0.001);5年间,7 d内接受检测的分别为673例(78.3%)、831例(76.9%)、936例(77.9%)、1088例(82.9%)和1140例(83.4%)。结论吉林省近年来新发现HIV/AIDS病例CD4的检测比例无明显上升趋势。应采取措施扩大HIV/AIDS主动咨询检测覆盖面,尽早发现更多的感染者,及时进行CD4检测,从而更早地采取相应的治疗措施。Objective To analyze the status of the first CD4+T Lymphocytes detection in newly confirmed HIV/AIDS cases in Jilin Province from 2014 to 2018,so as to provide scientific basis for the prevention and control of AIDS.Methods Each year,the online direct reporting case report card is downloaded in January,and the follow-up management database is downloaded in July.SPSS 25.0 software is used for data analysis.Results From 2014 to 2018,the proportion of newly discovered HIV/AIDS patients undergoing the first CD4 cell test showed an increasing trend(P<0.05).The median of the first CD4 count of AIDS patients in 5 years was 128.5,80.0,83.0,71.0,and 63.0,respectively.There was statistical significance on the differences among groups with different ages,education levels,occupations,marital status and transmission routes in the first CD4 test(P<0.001).During the 5 years,673 cases(78.3%),831 cases(76.9%),936 cases(77.9%),1088 cases(82.9%),and 1140 cases(83.4%)were tested within 7 days.Conclusion In recent years,the detection rate of CD4 in newly discovered HIV/AIDS cases in Jilin Province showed no obvious rising trend.Measures should be taken to expand the coverage of HIV/AIDS counselling and testing,to find more infected people as soon as possible,and to conduct CD4 testing in time,so as to take corresponding treatment measures earlier.
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