广西儿童新型冠状病毒肺炎11例临床分析  

Clinical analysis of 11 pediatric patients with 2019 corona virus disease in Guangxi

作　　者：代艳[1] 唐宁宁 徐帆[2] 叶琨[3] 蒋莉[2] 唐慧荷 唐芬 黄光怡 蒿艳蓉[4] 肖和卫[5] 王耀菊[1] 梁珍花[1] 钟晓刚[6] 马刚[6] 温志红[1] DAI Yan;TANG Ning-ning;XU Fan(Department of Paediatrics, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China)

机构地区：[1]广西壮族自治区人民医院儿科,南宁530021 [2]广西壮族自治区人民医院眼科,南宁530021 [3]广西壮族自治区人民医院肾内科,南宁530021 [4]广西壮族自治区人民医院肿瘤科,南宁530021 [5]广西壮族自治区人民医院科研部,南宁530021 [6]广西壮族自治区人民医院新冠肺炎防控指挥部

出　　处：《中国临床新医学》2020年第11期1149-1152,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的探讨新型冠状病毒肺炎患儿的临床特征及预后。方法回顾性分析2020-01-19~2020-03-11期间诊断为新型冠状病毒肺炎并集中收治于广西壮族自治区人民医院的11例住院患儿的临床资料。结果共纳入4例无症状患儿和7例普通型患儿,均为聚集性发病。肺部典型CT影像表现为磨玻璃阴影,经治疗后全部吸收。5例<3岁患儿均发现大便病毒核酸持续阳性,最长持续41 d;4例血清肌酸激酶同工酶水平升高2倍以上。新型冠状病毒肺炎母亲乳汁中病毒核酸阴性。结论新型冠状病毒肺炎患儿临床表现较轻,但对3岁以下儿童需警惕心肌损伤及粪口传播的可能。Objective To explore the clinical characteristics and prognosis of pediatric patients with 2019 corona virus disease(COVID-19).Methods The clinical data of 11 children with COVID-19 and admitted to the People′s Hospital of Guangxi Zhuang Autonomous Region during January 19,2020 and March 11,2020 were retrospectively analyzed.Results A total of 4 asymptomatic and 7 mild pediatric patients were included,all of whom appeared clustering occurrence.The typical CT images of the lungs was ground-glass opacity,which was completely absorbed after treatment.Five pediatric patients under 3 years old were found to be continuously positive for stool virus nucleic acid,lasting for 41 days at most.The levels of serum creatine kinase isoenzyme in 4 cases were more than 2 times higher than the normal value.The viral nucleic acid in the breast milk of the COVID-19 mother was negative.Conclusion The clinical manifestations of the pediatric patients with COVID-19 are mild.However,more attention should be paid to the possibilities of ongoing myocardial damage and fecal-oral transmission in the children under 3 years old.

关 键 词：新型冠状病毒肺炎 儿童 心肌损伤 粪口传播 

分 类 号：R563.1[医药卫生—呼吸系统]