A Chromosome-Level Genome Assembly of Garlic (Allium sativum) Provides Insights into Genome Evolution and Allicin Biosynthesis  

作　　者：Xiudong Sun Siyuan Zhu Ningyang Li Yi Cheng Jing Zhao Xuguang Qiao Li Lu Shiqi Liu Yanzhou Wang Chan Liu Benping Li Wu Guo Shuang Gao Zemao Yang Fu Li Zheng Zeng Qing Tang Yupeng Pan Mengjiao Guan Jian Zhao Xiaomi ng Lu Huanwe n Meng Zhenlin Han Chun she ng Gao Wenkai Jiang Xing Zhao Shilin Tian Jianguang Su Zhihui Cheng Touming Liu 

机构地区：[1]Shandong Agricultural University,Tai'an 271018,China [2]Institute of Bast Fiber Crops,Chinese Academy of Agricultural Sciences,Changsha 410205,China [3]Northwest A&F University,Yangling 712100,China [4]Novogene Bioinformatics Institute,Beijing 100083,China [5]School of Pharmaceutical Sciences,Wuhan University,Wuhan 430071,China

出　　处：《Molecular Plant》2020年第9期1328-1339,共12页分子植物（英文版）

基　　金：supported by grants from the National Key R&D Program of China(2016YFD040024);the Agricultural Science and Technology Innovation Program of China(CAAS-ASTIP-lBFC);the National Natural Science Foundation of China(31772323,31871678,and 31972000).

摘　　要：Garlic,an economically important vegetable,spice,and medicinal crop,produces highly enlarged bulbs and unique organosulfur compounds.Here,we report a chromosome-level genome assembly for garlic,with a total size of approximately 16.24 Gb,as well as the annotation of 57561 predicted protein-coding genes,making garlic the first Allium species with a sequenced genome.Analysis of this garlic genome assembly reveals a recent burst of transposable elements,explaining the substantial expansion of the garlic genome.We examined the evolution of certain genes associated with the biosynthesis of allicin and inulin neoseries-type fructans,and provided new insights into the biosynthesis of these two compounds.Furthermore,a large-scale transcriptome was produced to characterize the expression patterns of garlic genes in different tissues and at various growth stages of enlarged bulbs.The reference genome and large-scale transcriptome data generated in this study provide valuable new resources for research on garlic biology and breeding.

关 键 词：garlic genome genome evolution ALLICIN inulin neoseries-type fructans expression profiling 

分 类 号：Q78[生物学—分子生物学]