Sensitivity enhancement of WS2-coated SPR-based optical fiber biosensor for detecting glucose concentration  

作　　者：Yun Cai Wei Li Ye Feng Jian-Sheng Zhao Gang Bai Jie Xu Jin-Ze Li 蔡云;李卫;冯烨;赵建胜;白刚;许杰;李金泽(College of Electronic and Optical Engineering&College of Microelectronics,Nanjing University of Posts and Telecommunications,Nanjing 210023,China;State Key Laboratory of Millimeter Waves,Southeast University,Nanjing 210093,China;State Key Laboratory of Luminescent Materials and Devices,South China University of Technology,Guangzhou 510641,China;Research Center of Optical Communications Engineering&Technology,Nanjing 210023,China)

机构地区：[1]College of Electronic and Optical Engineering&College of Microelectronics,Nanjing University of Posts and Telecommunications,Nanjing 210023,China [2]State Key Laboratory of Millimeter Waves,Southeast University,Nanjing 210093,China [3]State Key Laboratory of Luminescent Materials and Devices,South China University of Technology,Guangzhou 510641,China [4]Research Center of Optical Communications Engineering&Technology,Nanjing 210023,China

出　　处：《Chinese Physics B》2020年第11期283-289,共7页中国物理B（英文版）

基　　金：Project supported by the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20171442);the China Postdoctoral Science Foundation(Grant No.2018T110480);the Open Foundation of State Key Laboratory of Millimeter Waves,China(Grant No.K202003);the Open Foundation of State Key Laboratory of Luminescent Materials and Devices,China(Grant No.2020-skllmd-03);the Fund from the Research Center of Optical Communications Engineering&Technology,Jiangsu Province,China(Grant No.ZXF201904).

摘　　要：In this paper,we propose a theoretical model of the surface plasmon resonance-based optical fiber biosensor for detecting glucose concentration.The Au/ZnO/WS2 multilayer film is coated around optical fiber.Compared with the conventional surface plasmon resonance sensor,WS2 material can increase the sensitivity of the biosensor.The absorption capacity of WS2 is used to load glucose oxidase by forming a sensitive area to recognize glucose.Refractive index of the solution is calculated and then the concentration of the glucose can be obtained by the correspondence between refractive index and glucose concentration.The highest sensitivity of the SPR biosensor with a structure of 40-nm Au/5-nm ZnO/14 layers of WS2 is 4310 nm/RIU.The proposed WS2-based SPR fiber biosensor has a unique effect on the detection of glucose concentration.It is expected to have potential applications in future medical blood glucose concentration detection.

关 键 词：surface plasmon resonance optical fiber BIOSENSOR GLUCOSE 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置] TN253[自动化与计算机技术—控制科学与工程]